Find 211 hotels in Santa Cruz

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Check hotel availability in Santa Cruz

25 Dec - 26 Dec
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Check prices in Santa Cruz for tonight, 25 Dec - 26 Dec
26 Dec - 27 Dec
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Most frequently booked hotels in Santa Cruz

DoubleTree by Hilton Iquitos

DoubleTree by Hilton Iquitos

5 out of 5
Napo 258 Iquitos
137.58 km from city centre
The price is €123 per night
€123
27 Dec - 28 Dec
Our customers tell us that they can't get enough of the helpful staff at DoubleTree by Hilton Iquitos. During your stay, you're just a quick walk from Plaza de Armas. Free WiFi in public areas, an outdoor pool and a restaurant are available.
Pool
Spa
Victoria Regia Hotel

Victoria Regia Hotel

4 out of 5
Ricardo Palma 252 Iquitos Loreto
137.14 km from city centre
The price is €52 per night
€52
26 Dec - 27 Dec
During your stay at Victoria Regia Hotel, you're just a quick walk from Tapiche Reserve. Features include free breakfast, free WiFi in public areas and free self-parking.
Pool
Breakfast included
El Dorado Classic Hotel

El Dorado Classic Hotel

3 out of 5
Napo 362 Iquitos Loreto
137.52 km from city centre
The price is €48 per night
€48
3 Jan - 4 Jan 2026
During your stay at El Dorado Classic Hotel, you're just a quick walk from Iquitos Cathedral. Enjoy features like free breakfast and free WiFi in public areas, plus an indoor pool.
Pool
Breakfast included
Hotel de Turistas Iquitos

Hotel de Turistas Iquitos

3 out of 5
Napo Iquitos Loreto
137.61 km from city centre
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During your stay at Hotel de Turistas Iquitos, you're just a quick walk from Tarapaca Boardwalk. You'll find features such as free breakfast and free WiFi in public areas, plus 2 restaurants.
Pool
Breakfast included
CASA BLANCA HOTEL

CASA BLANCA HOTEL

3 out of 5
446 Jorge Chavez Iquitos Loreto
135.57 km from city centre
The price is €42 per night
€42
26 Dec - 27 Dec
During your stay at CASA BLANCA HOTEL, you'll be within walking distance of Allpahuayo Mishana Bed & Trees. You'll find features such as free breakfast and free WiFi in public areas, plus an outdoor pool.
Pool
Breakfast included
Hotel La Casona

Hotel La Casona

2.5 out of 5
Avenida Fitzcarrald 147 Iquitos Loreto
137.2 km from city centre
The price is €38 per night
€38
26 Dec - 27 Dec
During your stay at Hotel La Casona, you're just a quick walk from Tarapaca Boardwalk. You'll find features such as free WiFi in public areas, plus a coffee shop/cafe and a snack bar/deli.
Pet-friendly
Free WiFi
Studio 69

Studio 69

2.5 out of 5
Jr. Pevas 669 Iquitos Loreto
137.46 km from city centre
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Our customers tell us that they can't get enough of the helpful staff at Studio 69. During your stay, you're just a quick walk from Amazon Golf Course. Free breakfast, free WiFi in public areas and a bar are available.
Breakfast included
Free WiFi
Hotel Camu Camu

Hotel Camu Camu

3 out of 5
376 Jirón Putumayo Iquitos Loreto
137.34 km from city centre
The price is €21 per night
€21
26 Dec - 27 Dec
During your stay at Hotel Camu Camu, you're just a quick walk from Amazon Golf Course. Features include free WiFi in public areas and a coffee shop/cafe.
All-inclusive
Free WiFi
DORAL INN HOTEL

DORAL INN HOTEL

3 out of 5
220 Antonio Raimondi Iquitos Loreto
137.75 km from city centre
The price is €42 per night
€42
26 Dec - 27 Dec
During your stay at DORAL INN HOTEL, you're just a quick walk from Tarapaca Boardwalk. Free breakfast, free WiFi in public areas and dry cleaning service are available.
Breakfast included
Free WiFi
Hotel Fenix

Hotel Fenix

2.5 out of 5
Pasaje Angel Brusco 172-174 Iquitos Loreto
137.97 km from city centre
The price is €34 per night
€34
1 Jan - 2 Jan 2026
During your stay at Hotel Fenix, you'll be within walking distance of Clínica Tramazon Doctor Iquitos. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
Breakfast included
Parking included
Hotel Marañón

Hotel Marañón

3 out of 5
289 Jirón Nauta Iquitos Loreto
137.65 km from city centre
The price is €57 per night
€57
26 Dec - 27 Dec
During your stay at Hotel Marañón, you're just a quick walk from Plaza de Armas. Features include free breakfast and free WiFi in public areas, plus a restaurant.
Breakfast included
Free WiFi
Apart Hotel Casa Morey

Apart Hotel Casa Morey

4 out of 5
Calle Loreto 200 - Plaza Ramón Iquitos Loreto
137.88 km from city centre
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Our customers tell us that they can't get enough of the helpful staff at Apart Hotel Casa Morey. During your stay, you're just a quick walk from Clínica Tramazon Doctor Iquitos. Features include free breakfast and free WiFi in public areas, plus an outdoor pool.
Pool
Breakfast included
Muyuna Lodge

Muyuna Lodge

3 out of 5
140 Kms Upriver From Iquitos Fernando Lores Loreto
128.66 km from city centre
The price is €549 per night
€549
13 Jan - 14 Jan 2026
Features at Muyuna Lodge include free breakfast and WiFi in public areas, plus a restaurant.
Breakfast included
All-inclusive
Hospedaje Las Amazonas

Hospedaje Las Amazonas

2.5 out of 5
Calle Las Amazonas c/c Calle Señor San Juan Bautista Iquitos
133.12 km from city centre
The price is €17 per night
€17
26 Dec - 27 Dec
With your stay at Hospedaje Las Amazonas, you'll be connected to the convention centre and within walking distance of Plaza José Abelardo Quiñones. Enjoy features like free WiFi in public areas and a free manager's reception, plus a bar.
Free WiFi
Business services
Treehouse Lodge

Treehouse Lodge

2.5 out of 5
Located on the beautiful black waters Saquena
118.32 km from city centre
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Features at Treehouse Lodge include free breakfast and a round-trip airport shuttle, plus a restaurant.
Breakfast included
Free airport shuttle
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Exploring Santa Cruz

The city of Santa Cruz has some interesting things to see and do. Popular attractions in and around Santa Cruz include:

  • Pacaya-Samiria National Reserve
  • Huallaga River

When is the Best Time to Explore Santa Cruz?

If you're wondering when is the best time of year to visit Santa Cruz, you may find this information about seasonal weather helpful when you are organising your getaway. The warmest months in Santa Cruz are typically September and October, whereas the coldest months are usually July and June. The months with the most rain are March and April, whereas August and July have the least.

Here's an overview on how much rain you can expect and what the temperatures are going to be like:

  • From January to March, the average daytime temperature is 30°C and at night it is 22°C. Seasonal average rainfall is 975 mm.
  • If you visit between April and June, you can expect an average temp of 30°C during the day and 21°C at night. Average rainfall during this season is 815 mm.
  • The daytime average temp from July to September is 33°C and the night-time average is 21°C. Average precipitation for this season is 431 mm.
  • Between October and December, the average temp during the day is 32°C and 22°C at night. Seasonal average rain is 731 mm.
  • The average annual rainfall in Santa Cruz is 2952 mm.

Santa Cruz hotels essential information

Accommodation
211 hotels
Lowest Price
€17
Highest Price
€549
Popular hotels
DoubleTree by Hilton Iquitos, Victoria Regia Hotel, El Dorado Classic Hotel, Hotel de Turistas Iquitos, CASA BLANCA HOTEL, Hotel La Casona, Studio 69, Hotel Camu Camu, DORAL INN HOTEL, Hotel Fenix, Hotel Marañón, Apart Hotel Casa Morey, Muyuna Lodge, Hospedaje Las Amazonas, Treehouse Lodge

Areas of Santa Cruz