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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Classic architecture with a grand entrance and evenly spaced windows.
Relax in a classic room with a large pool table, elegant curtains, and a chandelier.
Enjoy a luxurious bar experience with a curved countertop, comfortable seating, and a vibrant mural.
Experience the grandeur of our multi-level atrium, featuring a basketball court and balcony with a railing.
Relax by the pool surrounded by a comfortable seating area and natural light.

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • St. Louis Union Station
    ‪6 min walk‬
  • Enterprise Center
    ‪6 min walk‬
  • Busch Stadium
    ‪14 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(66 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

8.4 out of 10
Very good
(18 reviews)
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(23 reviews)
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.0 out of 10
Wonderful
(20 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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Relax in the elegant lobby, featuring a comfortable seating area with a sofa and armchairs, a staircase, and a chandelier.

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  • Pet-friendly
  • Free WiFi
  • Restaurant
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4.2 out of 5, Very good, (3914)
The price is €155
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includes taxes & fees
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About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
This smoke-free hotel features an indoor pool, a restaurant, and a fitness center. WiFi in public areas is free. Additionally, a bar/lounge, a steam room, and a coffee shop/cafe are onsite. Change of towels is available on request.
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from City Museum. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
  • Free WiFi
  • Drinking and dining options include a coffee shop, a restaurant, and a bar/lounge
  • Cooked-to-order breakfast served daily for a fee
  • Valet parking available for a fee
  • Take a swim in the indoor pool
  • Services include dry cleaning/laundry, a concierge, and luggage storage
  • Onsite recreation includes a gym and a steam room
  • Guests have great things to say about the helpful staff and the clean accommodations
  • Within a 10-minute walk of City Museum and Enterprise Center
  • Dogs welcome for a fee
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

For a fee, guests can enjoy cooked-to-order breakfast daily from 6:30 AM to 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Payment types at the property

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 927 out of 1283 reviews
Rating 8 - Good. 191 out of 1283 reviews
Rating 6 - Okay. 75 out of 1283 reviews
Rating 4 - Poor. 40 out of 1283 reviews
Rating 2 - Terrible. 50 out of 1283 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

6/10 Okay

Jessica

Travelled with partner
Liked: Cleanliness, amenities
Disliked: Staff & service
Looks good and the toiletries brand is amazing
Stayed 1 night in Apr 2025

10/10 Excellent

Richard, Hickory

Stayed 1 night in Apr 2025

10/10 Excellent

Moe

Stayed 3 nights in Apr 2025

10/10 Excellent

Joni

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular restaurant, comfortable room, good museum, and it feels safe. The elevator has keyed access to each floor.
Stayed 2 nights in Apr 2025

8/10 Good

Fran

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Repeat Customer

This was our 2nd stay which speaks volumes! We love this place. It is upscale but relaxed. Historic but modern. Great location in walking distance of many attractions, but quiet. Clean. So Clean. I feel very comfortable walking around the room without shoes. Just a couple issues I will note...no after hours room service or even vending to get a snack or drink. And, only 1 roll of toilet paper. I think 2 rolls would have made us less nervous.😉
Stayed 1 night in Apr 2025

6/10 Okay

Siegfried

Liked: Cleanliness, amenities, property conditions & facilities
Bar service was very slow. Staff didn’t tell us there was a coffee shop.
Stayed 2 nights in Apr 2025

8/10 Good

Heather

Liked: Cleanliness, property conditions & facilities
This hotel has a lot of potential. It’s in a good area of the city. The hotel itself is so fun bright colored wallpaper art all over the place pool hot tub saunas pool tables literally has something for everybody. The front desk staff was OK. The valet attendant were fantastic all in all enjoyed the trip
Stayed 2 nights in Apr 2025

10/10 Excellent

Elia

Liked: Cleanliness, staff & service, property conditions & facilities
Me gusto mucho la atencion al cliente y el progecionalizmo. Gracias
Stayed 2 nights in Apr 2025

10/10 Excellent

Sandra

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our two nights at this hotel. The property was nice and we were able to walk to Enterprise stadium easily.
Stayed 2 nights in Apr 2025

10/10 Excellent

Hilary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved everything! Will be back!

We will be coming back! We absolutely loved the hotel. From the rooms (we had a Deluxe King Suite) to the restaurants to the huge art museum…it did not disappoint. It was also within walking distance to our event at Enterprise Center. Staff were very friendly. Although we didn’t get in, the pool and hot tub both were large and looked nice. They also have two huge weight/workout rooms, treatment rooms, steam rooms, etc.
Stayed 1 night in Apr 2025

8/10 Good

Kenda

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Andrea, Du Quoin Illinois

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I stayed at this hotel for the stl go marathon and absolutely loved it! Super close to the start/finish so that was convenient. The hotel itself was beautiful and unique. From the art, to the amenities, and staff! Ugh it was all perfect. I will be staying here again next time I’m in town. 10/10!
One of the art galleries
View from the hotel window
Stayed 1 night in Apr 2025

10/10 Excellent

Samuel

Liked: Cleanliness, staff & service, property conditions & facilities
It’s easy to walk to most every venue I go to downtown. The hotel is amazingly beautiful.
Stayed 1 night in Apr 2025

2/10 Terrible

Steve

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort
We checked in the rain, not realizing they didn’t have a car port area or porters with umbrellas. Signage was very confusing outside and inside. The 1st room we were given had no electricity. The second room we were given had stains on the walls, carpet and bedding-which we suspected was mold. There was also someone’s medical patch on the shower floor. When my wife went to look at it closer, the shower floor had disgusting build up of something along the sides. My wife felt sick and we had already gotten ready for bed so when we called about the bed they said house cleaning was gone and we could move to another room by coming back downstairs and going through the same 30 minute process we had already done. Yes we should have checked the room before doing anything, but we’ve never had a boutique hotel that wasn’t more than acceptable. My wife slept in the chair, I slept in my clothes on top of other clothes on top of the bedding. The elevator appeared to have wine thrown all over it when we checked in, but was cleaned in the morning. They did refund the additional two nights we were scheduled to stay in, so I’m thankful for that. But we were told the one night “stay” would also be refunded which didn’t happen. This was one of the worst experiences I’ve had in my significant travel history.
Stayed 2 nights in Apr 2025

8/10 Good

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Great place in St. Louis.
Stayed 1 night in Apr 2025

10/10 Excellent

Kenneth

Liked: Cleanliness, staff & service, property conditions & facilities
No parking except valet
Stayed 1 night in Apr 2025

10/10 Excellent

Eric

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a really nice place to stay. Me and my wife enjoyed the hotel, pool, dinning, and the staff. We are going to go back. hopfuly for my birthday. Thank you hotel 21c!
Stayed 2 nights in Apr 2025

10/10 Excellent

Michelle

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing
Stayed 2 nights in Apr 2025

10/10 Excellent

Emily

Travelled with family
Liked: Staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Apr 2025

10/10 Excellent

Jennifer

Travelled with family, Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I always love staying at this hotel! The decor is beautiful and the drinks and food are top notch!
Stayed 1 night in Apr 2025

6/10 Okay

Sandra

Stayed 4 nights in Apr 2025

8/10 Good

Katherine L

Travelled with family
Liked: Cleanliness, room comfort
Disliked: Property conditions & facilities

Beautiful hotel, disappointing service

I wish I had nothing but glowing things to say, but I’m so disappointed about something that happened during our stay. We arrived fairly late in the day and all I wanted was to shower. The shower in our room was broken (the pull to transfer water from the tub to shower was missing). We called the front desk and requested it be fixed or we be moved. We were told they would send engineering. 30 minutes later I called back to ask for an ETA. I was told they’d send them right up. Another 30 minutes later we called to say don’t bother as it was then after 10pm and my son needed to go to sleep. I then did my best to bathe, but it was rather uncomfortable (actually painful at times) trying to crouch under the tub faucet to get clean. It did not feel like the front desk took our request seriously at all. I felt, in fact, quite dismissed when a shower seems not too much to ask at any hotel, let alone one like 21C. I will not be returning to this or any other 21C hotel.
Stayed 2 nights in Apr 2025

10/10 Excellent

KARI

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Apr 2025

10/10 Excellent

Anthony

Business traveller, Travelled with family, Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Apr 2025

10/10 Excellent

John

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfection!
Stayed 2 nights in Apr 2025