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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Restaurant
Massages
Exterior
Exterior
Bar (on property)

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, City Museum
    ‪6 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪19 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(77 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

In-room safe, desk, laptop workspace, blackout curtains

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Loft, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout curtains

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
This smoke-free hotel features an indoor pool, a restaurant, and a fitness center. WiFi in public areas is free. Additionally, a bar/lounge, a steam room, and a coffee shop/cafe are onsite. Change of towels is available on request.
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from City Museum. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
  • Free WiFi
  • Drinking and dining options include a coffee shop, a restaurant, and a bar/lounge
  • Cooked-to-order breakfast served daily for a fee
  • Valet parking available for a fee
  • Take a swim in the indoor pool
  • Services include dry cleaning/laundry, a concierge, and luggage storage
  • Onsite recreation includes a gym and a steam room
  • Guests have great things to say about the clean accommodations and the location
  • Within a 10-minute walk of City Museum and Enterprise Center
  • Dogs welcome for a fee
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness center. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business center and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

For a fee, guests can enjoy cooked-to-order breakfast daily from 6:30 AM to 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Awards and affiliations

Eco-Certified Property
This property participates in Green Key Global, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Payment types at the property

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Reviews

21C Museum Hotel St Louis Reviews

9.0

Wonderful

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness
Rating 10 - Excellent. 1081 out of 1501 reviews
Rating 8 - Good. 224 out of 1501 reviews
Rating 6 - Okay. 97 out of 1501 reviews
Rating 4 - Poor. 45 out of 1501 reviews
Rating 2 - Terrible. 54 out of 1501 reviews

Reviews

10/10 Excellent

Whitney

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful stay!
Stayed 1 night in Sep 2025

8/10 Good

Jeffrey, Springfield

Travelled with partner
The restaurant and coffee shop servers and valets were great- others seemed to be quiet quitting and disinterested
Stayed 2 nights in Sep 2025

8/10 Good

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Didn't have our room ready until after check in time advertised..
Stayed 1 night in Sep 2025

6/10 Okay

Blake D.

This is not the luxury hotel I expected. From the moment I walked in I see that it doesn’t look anyone has vacuumed for a week. Walls are banged up and in need of paint. Area not great either. Would not choose again
Stayed 1 night in Sep 2025

10/10 Excellent

Catherine

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jun 2025

6/10 Okay

Chante

Travelled with family
Liked: Cleanliness
Disliked: Amenities, property conditions & facilities
Valet was rude, tv did not work and when we called, they said they’d send someone up to fix it and did not, the AC did not work either. Also there were hairs in the shower that were there when we checked in. Will not be staying here again.
Stayed 1 night in Sep 2025

10/10 Excellent

Blane

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent

Beautiful hotel. I loved the art museum. The restaurant was really great. The gym and pool were amazing. I highly recommend.
Stayed 2 nights in Sep 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Get away trip with bae

It was nice. Great amenities and lots to do. I loved the museum
Stayed 2 nights in Sep 2025

6/10 Okay

Nicole

Travelled with group
Disliked: Staff & service
An okay area. Our body was was never refilled and when asking about early check in I spoke with 3 different people who all told me different things.
Stayed 2 nights in Sep 2025

10/10 Excellent

Leslie

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel in a historic YMCA building downtown. First class interiors, art collection, ambiance, and rooms. The room was small but well appointed. Very quiet. All amenities (no microwave), including wonderful Italian coffee machine. We also had an amazing cocktail hour with the bartender in the lobby. He knows his craft very well. We’ll be starting here often in the future.
Stayed 2 nights in Sep 2025

10/10 Excellent

Casey

Liked: Amenities, property conditions & facilities
Amazing staff, clean!
Stayed 1 night in Sep 2025

10/10 Excellent

Marquis

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Sep 2025

10/10 Excellent

Stephen

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Very interesting property. Enjoyed the stay.
Stayed 1 night in Sep 2025

10/10 Excellent

Reginald

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice place
Stayed 3 nights in Sep 2025

10/10 Excellent

Jemma

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

margaret

Travelled with family
Liked: Amenities
Fantastic property with great device
Stayed 1 night in Sep 2025

6/10 Okay

Talisha

Stayed 1 night in Sep 2025

10/10 Excellent

Lee

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Sep 2025

8/10 Good

Steven

Business traveller
Liked: Cleanliness, staff & service, room comfort
Stayed 3 nights in Jul 2025

10/10 Excellent

Larry

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

A literal museum

A terrific hotel created from what once was the YMCA. (Be sure to take a look at the exquisite tile work in the downstairs swimming pool.) There’s fascinating modern art, including a large gallery on the second floor. But beware that the hotel is on a desolate street of abandoned buildings so be prepared to pay high valet fees for parking or take Uber everywhere.
Stayed 3 nights in Sep 2025

10/10 Excellent

Matthew

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Aug 2025

10/10 Excellent

Sarah

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the art and the building itself. Bed sheets weren’t as clean and the pillows weren’t comfortable. The towels in the bathroom were frayed.
Stayed 1 night in Sep 2025

10/10 Excellent

Kevin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Kerry

Liked: Cleanliness, amenities
Great idea with the museum, fantastic older building with so much chsracter.
Stayed 1 night in Aug 2025

10/10 Excellent

Robyn J

Stayed 1 night in Aug 2025