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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Free Wi-Fi
  • Air-conditioning

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Place, St. Louis Zoo
    ‪23 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.6 out of 10
Exceptional
(14 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.6 out of 10
Exceptional
(34 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.2 out of 10
Wonderful
(5 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(18 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

Standard Room

  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bed
  • Free Wi-Fi

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 2 Queen Beds

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 2 Queen Beds

9.6 out of 10
Exceptional
(80 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

Similar properties

Lobby
Hampton Inn & Suites St. Louis/South I-55
St. Louis
  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.8 out of 5, Exceptional, 1,003 reviews
The price is €105
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn & Suites St. Louis/South I-55

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Along with an indoor pool, this smoke-free hotel has a 24-hour fitness center and a business center. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, a 24-hour front desk, a front-desk safe, and a banquet hall are onsite. Housekeeping is available on request.
Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with safes and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
The free breakfast at Holiday Inn Express & Suites St. Louis South - I-55 by IHG gets high marks from our customers. During your stay, you're just a quick walk from Barnes Jewish South Campus. You'll find features like free WiFi in public areas and free self parking, plus an indoor pool.
  • Free buffet breakfast served daily
  • Free WiFi
  • Free self parking
  • Take a swim in the indoor pool
  • Amenities include a front-desk safe, a business center, and meeting rooms
  • Onsite recreation includes a 24-hour gym
  • Guests have great things to say about the helpful staff and the breakfast
  • 7 minutes by foot from Barnes Jewish South Campus and a 4-minute drive from BounceU of St. Louis
Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers its guests an indoor pool and a 24-hour fitness center. Public spaces have free WiFi. A business center and meeting rooms are available. Free breakfast is served daily. The business-friendly Holiday Inn Express & Suites St. Louis South - I-55 by IHG also features a vending machine, a front-desk safe, and an elevator. Self parking is free.

This St. Louis hotel is smoke free.

Guests are served free buffet breakfast daily from 6:00 AM to 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Free cribs (infant beds)!

Payment types at the property

Important information

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Pool access available from 8 AM to 10 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 805 out of 1006 reviews
Rating 8 - Good. 141 out of 1006 reviews
Rating 6 - Okay. 38 out of 1006 reviews
Rating 4 - Poor. 15 out of 1006 reviews
Rating 2 - Terrible. 7 out of 1006 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was wonderful and the accommodations were cleani, quiet and just what I needed.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Adam

Liked: Cleanliness, amenities, property conditions & facilities
Great stay
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Tracy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Overnight Mother's Day trip was a great stay at the Holiday Inn Express I55 South location. Normally would lodge at Hampton Inn next door when I visited St. Louis but definitely found better at Holiday Inn express. Staff was very nice and breakfast was a big winner with Bacon 😉
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good breakfast selection, clean room. Overall clean place. Friendly and helpful staff. Pool is a little small so keep that in mind when traveling with kids, but it was a nice pool!
Stayed 3 nights in May 2026
Verified review

10/10 Excellent

Kelsey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Desk staff was very friendly, room was nice and clean, kids loved the pool, breakfast was great!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Jamie

Liked: Cleanliness, staff & service
Clean room, friendly staff.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

George

Liked: Cleanliness, staff & service, amenities
Clean rooms, great friendly staff, very good breakfast with lots to choose from
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

ARIANNE

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brand new hotel great beds and quiet despite it being sold out the night we stayed.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Megan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, location was ideal for activities in St Louis, complimentary parking and warm cookies at night!
Stayed 4 nights in Mar 2026
Verified review

10/10 Excellent

Shardae

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was amazing. Staff so welcoming and friendly. Cookie hour, was a sweet gesture.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Denise

Liked: Cleanliness, staff & service, property conditions & facilities
We were very happy with our stay!!! It was perfect distance from where we were playing in a tournament. Close to places to eat and services. The staff were exceptionally helpful and friendly. Thank you for our stay
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

HEATHER

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place was clean, the pool was functional, the food was decent, and my kids favorite part was the cookie hour! Will definitely pick this hotel when we come back to the St Louis area!
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, amenities
The room is clean, the bed and pillows are super comfy and the breakfast is great! I travel to the area a few times a year for work and this is my new favorite place to stay.
Stayed 4 nights in Feb 2026
Verified review

10/10 Excellent

Trista

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was great.
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was so kind and helpful. Breakfast was delicious. We really loved the fluffy scrambled eggsa and the bean to brew coffee machine. Will definitely stay again.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

James

Clean room, location, excellent staff
Stayed 4 nights in Dec 2025
Verified review

10/10 Excellent

Mary C

Liked: Cleanliness, staff & service, property conditions & facilities
Breakfast was great, quite a variety of food and drink. Staff were all kind and thoughtful. Real treat was warm cookies and milk in evening!!
Stayed 3 nights in Apr 2026
Verified review

10/10 Excellent

Janice

Liked: Cleanliness, staff & service, amenities
Enjoyed the cleanliness and comfort of the bed and room and the friendly staffand the freshly roasted coffeecofrrroascoffee
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Mitch

Liked: Cleanliness, staff & service, property conditions & facilities
It was great!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Guillermo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was perfect . Zero complains
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Anita

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean and staff was friendly.
Stayed 2 nights in Nov 2025
Verified review

10/10 Excellent

Jami

Liked: Cleanliness, staff & service, property conditions & facilities
Great
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was fresh, hot, and delicious. Various choices from cinnamon rolls and pancakes to cheese omelettes and sausage to cereal and yogurt. The room was clean.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

LESLIE

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a quick stay but one very appreciated thing was security at the end of the street checking visitors approaching hotels late at night. Kept me from worrying about cars being broken in to overnight.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Pamela

Liked: Cleanliness, amenities, property conditions & facilities
Staff is very nice! The rooms are clean and comfortable.
Stayed 1 night in Jan 2026