Find Des Moines - Destin Flights (DSM - VPS)

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Des Moines to Destin Flight Information
Origin airport IATA code
DSM
Destination airport IATA code
VPS

Destin Flight Information

Traveling From
Des Moines
Origin Airport IATA Code
DSM
Traveling To
Destin
Destination Airport IATA Code
VPS
Number of Airlines Serving
Available Airlines
Distance
Direct Flight Time
Flight Price

Car Hire offers in Destin

Hotels in Destin

The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa

5 out of 5
200 Henderson Resort Way Destin FL
Stay at this luxury resort in Destin. Enjoy free Wi-Fi, 2 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
9.2/10 Wonderful! (1,004 reviews)
All around great resort for any occasion!!!

Reviewed on 23 Feb 2026

Opens in a new windowThe Henderson Beach Resort & Spa
Homewood Suites by Hilton Destin

Homewood Suites by Hilton Destin

3 out of 5
14051 Emerald Coast Parkway Destin FL
Stay at this business-friendly hotel in Destin. Enjoy free breakfast, free parking and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,341 reviews)
Been here since December and it is by far, a great deal, great location, great staff, great amenities and huge clean rooms!

Reviewed on 23 Feb 2026

Opens in a new windowHomewood Suites by Hilton Destin
Home2 Suites By Hilton Destin

Home2 Suites By Hilton Destin

3 out of 5
14060 Emerald Coast Pkwy Destin FL
Stay at this hotel in Destin. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their reviews. Popular ...
8.8/10 Excellent! (1,008 reviews)
We have never stayed at this type of Hilton before. The room was spacious very clean.

Reviewed on 22 Feb 2026

Opens in a new windowHome2 Suites By Hilton Destin
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Comfort Inn & Suites Destin near Henderson Beach

Comfort Inn & Suites Destin near Henderson Beach

2.5 out of 5
4401 COMMONS DRIVE EAST Destin FL
Stay at this business-friendly hotel in Destin. Enjoy free breakfast, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (872 reviews)
Great over night stay!

Reviewed on 24 Feb 2026

Opens in a new windowComfort Inn & Suites Destin near Henderson Beach
SummerPlace Inn Destin

SummerPlace Inn Destin

3 out of 5
14047 Emerald Coast Pkwy Destin FL
Stay at this business-friendly hotel in Destin. Enjoy free Wi-Fi, free parking and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,212 reviews)
The hotel was clean, the staff was nice and the location to the restaurant s is awesome.

Reviewed on 23 Feb 2026

Opens in a new windowSummerPlace Inn Destin
Spark by Hilton Destin

Spark by Hilton Destin

3 out of 5
4415 Commons Dr E Destin FL
Stay at this business-friendly hotel in Destin. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...
8.6/10 Excellent! (728 reviews)
Staff was very friendly and helpful. The property was not a beach view as stated…we faced the back of the property with a pool view instead of what the listing stated when I booked with this hotel. The air filter in the room was very dirty and looked like it had not been changed in quite some time. ...

Reviewed on 17 Feb 2026

Opens in a new windowSpark by Hilton Destin
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

*Terms & Conditions: Etihad 4x BONUS+

Eligible to all ebookers BONUS+ members with stand-alone flight bookings made on ebookers’ website from 00:01 UTC 30 October 2015 through 23:59 UTC 1 November 2015 where the validating carrier is Etihad. Etihad multiplier (“Etihad Multiplier”) applies to the base of 1% BONUS+ earned on eligible flight bookings. Members will be issued an additional amount of BONUS+, equal to 4% (“Promotional Earn”) of the amount paid for each of the aforementioned bookings if the members were logged in to their BONUS+ account at the time of booking. If such a member has already earned the annual air cap in BONUS+, the member will not earn the Base Earn but will still earn the promotional BONUS+. In all of the above-mentioned cases, customers booking when logged in on the ebookers mobile application will earn triple the 2% Mobile Earn on the purchase price, totalling 8% earn. The earned promotional BONUS+ will expire if not redeemed within 60 calendar days from the date of issuance. Offer is non-transferrable and not redeemable for cash. The earned promotional BONUS+ will be deposited in your BONUS+ account at the time of booking. ebookers reserves the right to change, limit, or cancel the promotion in its sole discretion. See ebookers Terms and Conditions for additional applicable terms and conditions on: http://www.ebookers.ie/info/win?id=LoyaltyTerms

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.