Find Quito - Santa Cruz Island Flights from €125 (UIO - GPS)

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Selected fares from Quito to Santa Cruz Island

The lowest prices found within the past 7 days from Quito to Santa Cruz Island were €125 for one-way flights and €266 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, 7 Sep - Fri, 12 Sep
UIO
Mariscal Sucre Intl.
GPS
Seymour
€266 Return, found 1 day ago
€266
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, 7 Sep from Mariscal Sucre Intl. to Seymour, returning Fri, 12 Sep, priced at €266 found 1 day ago
Fri, 2 Jan - Sat, 10 Jan
UIO
Mariscal Sucre Intl.
GPS
Seymour
€266 Return, found 1 day ago
€266
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, 2 Jan from Mariscal Sucre Intl. to Seymour, returning Sat, 10 Jan, priced at €266 found 1 day ago
Sun, 12 Oct - Wed, 15 Oct
UIO
Mariscal Sucre Intl.
GPS
Seymour
€273 Return, found 2 days ago
€273
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, 12 Oct from Mariscal Sucre Intl. to Seymour, returning Wed, 15 Oct, priced at €273 found 2 days ago
Fri, 5 Sep - Sun, 7 Sep
UIO
Mariscal Sucre Intl.
GPS
Seymour
€283 Return, found 19 hours ago
€283
Return
found 19 hours ago
Select LATAM Airlines Group flight, departing Fri, 5 Sep from Mariscal Sucre Intl. to Seymour, returning Sun, 7 Sep, priced at €283 found 19 hours ago
Fri, 5 Sep - Mon, 8 Sep
UIO
Mariscal Sucre Intl.
GPS
Seymour
€288 Return, found 2 days ago
€288
Return
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, 5 Sep from Mariscal Sucre Intl. to Seymour, returning Mon, 8 Sep, priced at €288 found 2 days ago
Quito to Santa Cruz Island Flight Information
Origin airport IATA code
UIO
Destination airport IATA code
GPS
Number of flight options
2
Return price
€265
Average flight time
2 hours 3 mins

Best Days To Fly From UIO to GPS

Santa Cruz Island GPS Flight Information

Traveling From
Quito
Origin Airport IATA Code
UIO
Traveling To
Santa Cruz Island
Destination Airport IATA Code
GPS
Number of Airlines Serving
2
Available Airlines
LATAM Airlines Group
Distance
1324 km
Direct Flight Time
2 10
Flight Price
€266

Car Hire offers in Santa Cruz Island

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Hotels in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (348 reviews)
"The staff was amazing. Everyone was so thought full. The manger was also very helpful full. I would take this hotel anywhere I go if I could. Close to everything. There were little shops right down the road to eat or drink Thanks a lot. Russ, Yoko and Joshua."

Reviewed on 19 Jul 2025

Hotel Fiesta
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos, Puerto Ayora, Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.2/10 Wonderful! (10 reviews)
"amazing hotel and the best service the pool is the perfect spot to see seals, sea turtles, sting rays, sharks and pelicans , at night it’s quiet and the room was perfect. loved especially my balcony overlooking the docks."

Reviewed on 6 Jul 2025

El Barranco Galapagos
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
Stay at this 4-star B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (253 reviews)
"Amazing hotel. Ana and the rest of the staff were very friendly and kind. I greatly appreciate their hospitality and the amenities of the hotel. Very clean and comfortable. Great location right near ocean and short walk from restaurants and nature viewing. Can’t wait to come back!"

Reviewed on 17 Jun 2025

Hotel Cucuve
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Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (159 reviews)
"I only leave a 4 star review because I stayed for 5 days and the breakfasts were boring. Every day they offered the same thing, eggs, toast, or pancakes, cereal and strawberry yogurt. They don’t have a restaurant in the hotel and everything is far away. After the second day I was bored with the breakfast ..."

Reviewed on 29 Jun 2025

Hotel el descanso del Guia
Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton

4.5 out of 5
Km. 18 Via Puerto Ayora-Baltra Isla, Isla Santa Cruz, Santa Rosa, Galapagos
Stay at this 4.5-star luxury hotel in Santa Rosa. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Popular attractions Los Gemelos Sinkholes and Lava Tunnel ...
9.2/10 Wonderful! (49 reviews)
"The Royal Palm offers a truly immersive Galápagos experience—set inland on a stunning 100 acre property, far from the touristy feel of the ports. Recently under new ownership, the property is being refreshed: rooms are spacious and renovated, the pool has been redone, and quiet renovations are underway, ..."

Reviewed on 20 Apr 2025

Royal Palm Galapagos, Curio Collection Hotel by Hilton
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada, Puerto Ayora, Galapagos
Stay at this 4.5-star luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (86 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"

Reviewed on 31 Dec 2024

Finch Bay Galapagos Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Santa Cruz Island Airports

Other Flights to Santa Cruz Island

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*Terms & Conditions: Etihad 4x BONUS+

Eligible to all ebookers BONUS+ members with stand-alone flight bookings made on ebookers’ website from 00:01 UTC 30 October 2015 through 23:59 UTC 1 November 2015 where the validating carrier is Etihad. Etihad multiplier (“Etihad Multiplier”) applies to the base of 1% BONUS+ earned on eligible flight bookings. Members will be issued an additional amount of BONUS+, equal to 4% (“Promotional Earn”) of the amount paid for each of the aforementioned bookings if the members were logged in to their BONUS+ account at the time of booking. If such a member has already earned the annual air cap in BONUS+, the member will not earn the Base Earn but will still earn the promotional BONUS+. In all of the above-mentioned cases, customers booking when logged in on the ebookers mobile application will earn triple the 2% Mobile Earn on the purchase price, totalling 8% earn. The earned promotional BONUS+ will expire if not redeemed within 60 calendar days from the date of issuance. Offer is non-transferrable and not redeemable for cash. The earned promotional BONUS+ will be deposited in your BONUS+ account at the time of booking. ebookers reserves the right to change, limit, or cancel the promotion in its sole discretion. See ebookers Terms and Conditions for additional applicable terms and conditions on: http://www.ebookers.ie/info/win?id=LoyaltyTerms

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.