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Hampton Inn & Suites St. Louis/South I-55

2.5 star property

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Photo gallery for Hampton Inn & Suites St. Louis/South I-55

Lobby
Room
Fitness facility
Snack bar
Indoor pool

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning

Explore the area

View in a map
4200 Midamerica Lane, St. Louis, MO, 63129
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Place, St. Louis Zoo
    ‪23 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

1 King Bed Nonsmoking

  • Sleeps 2
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.8 out of 10
Exceptional
(41 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.6 out of 10
Exceptional
(15 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

View all photos for Two Queen Beds, Non-Smoking, Accessible

A hotel room with a bed, desk, chair, television, and a minibar.

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(28 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for One King Bed, Non-Smoking, Accessible

A hotel room with a large bed, two bedside lamps, a nightstand with a phone, and a door to another room.

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(22 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Studio, Accessible, Non Smoking

A hotel room with a bed, a desk with a telephone, a chair, a sofa, a lamp, and a painting on the wall.

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free Wi-Fi

2 Queen Beds Nonsmoking

  • Sleeps 4
  • Free Wi-Fi

View all photos for 2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.

2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

  • Sleeps 4
  • Free Wi-Fi

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Lobby
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  • Pet-friendly
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4.2 out of 5, Very good, 1,019 reviews
The price is €72
includes taxes & fees
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About this property

Hampton Inn & Suites St. Louis/South I-55

An indoor pool, a fitness center, and coffee/tea in a common area are available at this hotel. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, a business center, conference space, and dry cleaning are onsite.
Hampton Inn & Suites St. Louis/South I-55 offers 92 accommodations with safes and coffee/tea makers. 37-inch LCD televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

This St. Louis hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include complimentary weekday newspapers and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a fitness center.

Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision.

The free breakfast at Hampton Inn & Suites St. Louis/South I-55 gets high marks from our customers. During your stay, you're just a quick walk from Barnes Jewish South Campus. You'll find features like free WiFi in public areas and free self parking, plus an indoor pool.
  • Free buffet breakfast served daily
  • Free WiFi and wired Internet
  • Free self parking
  • Take a swim in the indoor pool
  • Amenities include free lobby newspapers, a front-desk safe, and a business center
  • Onsite recreation includes a gym
  • Guests have great things to say about the clean accommodations and the helpful staff
  • Just a 1-minute drive from Barnes Jewish South Campus and 9 minutes from Mississippi River
  • Cats and dogs welcome for a fee
Hampton Inn & Suites St. Louis/South I-55 offers its guests an indoor pool and a fitness center. A computer station is on site, and both WiFi and wired Internet are free in public spaces. A business center and a meeting room are available. Free breakfast is served daily. Event space at this hotel measures 753 square feet (70 square meters) and includes conference space. Hampton Inn & Suites St. Louis/South I-55 also features a vending machine, coffee/tea in a common area, and complimentary newspapers in the lobby. Self parking is free.
Guests are served free buffet breakfast daily from 6:00 AM to 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business centre
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay films

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 75 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 pets
  • Pets cannot be left unattended
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Payment types at the property

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Pool access available from 8 AM to 10 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Hampton Inn & Suites St. Louis/South I-55 Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 816 out of 1002 reviews
Rating 8 - Good. 134 out of 1002 reviews
Rating 6 - Okay. 27 out of 1002 reviews
Rating 4 - Poor. 5 out of 1002 reviews
Rating 2 - Terrible. 20 out of 1002 reviews

9.6/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

winnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Arlene

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I had a great stay. Clean rooms and friendly staff
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Alison

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The front desk attendant was very helpful and welcoming. I was impressed wit the cleanliness of our room and the hot breakfast options. Would definitely stay there again!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff and room was GREAT!!! Parking was great!! Room was clean and well stocked. Breakfast was good as always. Nice comfortable environment that makes you feel home away from home. We will be returning.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Deloris

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was clean. Staff was courteous. The breakfast was average for 3 star hotel.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Yvonne

The room was excellent and so was the staff.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Phyllis

Liked: Cleanliness, staff & service, amenities
Nice clean room spacious
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Josi

Liked: Cleanliness, staff & service, amenities
Fast check in. Nice staff. Clean and quiet room!!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Miliska

Liked: Cleanliness, staff & service, amenities
The room was clean, modern, and pleasant. Staff members were welcoming, respectful, positive, and helpful.
Stayed 1 night in Jan 2026
Verified

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025
Verified

8/10 Good

josh

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

kevin

Liked: Cleanliness, amenities, property conditions & facilities
The room was very much attended to. It was excellent. The biggest drawback was Internet. My wife felt a little close then because of the city view and not the Park view.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Manivannan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Parking is Safe, Cleanliness is Good. Hospitality is Appreciable.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Vicenta Fe

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I liked everything about this Hampton Inn, from the staff, room, amenities, breakfast, cleanliness, location and parking are all superb. Will definitely come back
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Franklin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Enjoyed our stay and would return.
Stayed 1 night in Mar 2025