Cheap flights from Middlesboro

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Middlesboro Flight Information
Origin airport IATA code
TYS

Sourcing the best flights from Middlesboro on ebookers

If you’re seeking a flight from Middlesboro, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from TYS. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from TYS

There are a few golden rules for keeping costs low when booking flights from Middlesboro. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Middlesboro, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from TYS. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Middlesboro

Holiday Inn Express Middlesboro by IHG

Holiday Inn Express Middlesboro by IHG

2.5 out of 5
1252 N 12th St Middlesboro KY
The price is €110 per night from 3 May to 4 May
€110
per night
3 May - 4 May
Our customers tell us that they enjoy the free breakfast at Holiday Inn Express Middlesboro by IHG. During your stay, you're just a quick walk from Middlesboro Mall. You'll find features such as free WiFi in public areas and free self-parking, plus an outdoor pool.
9.6/10 Exceptional! (718 reviews)
The rooms are clean and up to date. The beds were comfortable and easy to get into and out of. Their prices are reasonable.

Reviewed on 1 May 2026

Opens in a new windowHoliday Inn Express Middlesboro by IHG
Sleep Inn & Suites Middlesboro

Sleep Inn & Suites Middlesboro

2.5 out of 5
1260 N, 12th Street Middlesboro KY
The price is €91 per night from 26 May to 27 May
€91
per night
26 May - 27 May
Our customers tell us that they can't get enough of the free breakfast at Sleep Inn & Suites Middlesboro. During your stay, you'll be within walking distance of Cumberland Gap National Historical Park. You'll find features such as free WiFi in public areas and free self-parking, plus a gym.
9.2/10 Wonderful! (862 reviews)
We liked everything about the hotel.

Reviewed on 1 May 2026

Opens in a new windowSleep Inn & Suites Middlesboro
Suburban Studios Middlesboro

Suburban Studios Middlesboro

2 out of 5
1623 Cumberland Avenue Building B Middlesboro KY
The price is €79 per night from 31 May to 1 Jun
€79
per night
31 May - 1 Jun
During your stay at Suburban Studios Middlesboro, you're just a quick walk from Cumberland Gap National Historical Park. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
8.2/10 Very Good! (84 reviews)
The room was very clean, the bed was comfortable

Reviewed on 11 Apr 2026

Opens in a new windowSuburban Studios Middlesboro
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Econo Lodge Middlesboro

Econo Lodge Middlesboro

2 out of 5
1623 Cumberland Avenue Middlesboro KY
The price is €71 per night from 3 May to 4 May
€71
per night
3 May - 4 May
Our customers tell us that they can't get enough of the helpful staff at Econo Lodge Middlesboro. During your stay, you're just a quick walk from Cumberland Gap National Historical Park. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
7.4/10 Good! (461 reviews)
Very nice clean area, staff great & very friendly. Good selection of frozen breakfast sandwiches, fruit, yogurt,pastries, cereal , etc. And very good coffee!

Reviewed on 17 Apr 2026

Opens in a new windowEcono Lodge Middlesboro
Days Inn by Wyndham Jellico - Tennessee State Line

Days Inn by Wyndham Jellico - Tennessee State Line

2 out of 5
1417 5th Street Jellico TN
The price is €58 per night from 17 May to 18 May
€58
per night
17 May - 18 May
Our customers tell us that they can't get enough of the helpful staff at Days Inn by Wyndham Jellico - Tennessee State Line. During your stay, you'll be within walking distance of Indian Mountain State Park. Features include free breakfast, free WiFi in public areas and free self-parking. Some of the pet-friendly amenities that this property offers include food and water bowls and pet-sitting services.
7.2/10 Good! (1,001 reviews)
Definitely recommend and would stay here again if we needed to!

Reviewed on 1 May 2026

Opens in a new windowDays Inn by Wyndham Jellico - Tennessee State Line
Super 8 by Wyndham Williamsburg

Super 8 by Wyndham Williamsburg

2.5 out of 5
30 W Highway 92 Williamsburg KY
The price is €65 per night from 31 May to 1 Jun
€65
per night
31 May - 1 Jun
Our customers tell us that they can't get enough of the helpful staff at Super 8 by Wyndham Williamsburg. During your stay, you're just a quick walk from Briar Creek Park. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
5.6/10 (821 reviews)
This place was misrepresented on the internet. Not renovated in 2026. Filthy, amenities broken or non existent . Woman at desk called 911 when we complained about the uninhabitable rooms. Called heath department in Whitley county to file a complaint. Worst hotel EVER! Didn't stay at all it was so ...

Reviewed on 30 Apr 2026

Opens in a new windowSuper 8 by Wyndham Williamsburg
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.