Cheap flights from San Luis Obispo

Many airlines offer flexible change policies

Earn BONUS+ rewardsOpens in a new window on top of your airline points

Enjoy exclusive promotions on the ebookers app!

San Luis Obispo Flight Information
Origin airport IATA code
PRB

Sourcing the best flights from San Luis Obispo on ebookers

If you’re seeking a flight from San Luis Obispo, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from PRB. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from PRB

There are a few golden rules for keeping costs low when booking flights from San Luis Obispo. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from San Luis Obispo, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from PRB. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near San Luis Obispo

Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

3 out of 5
1631 Monterey St San Luis Obispo CA
The price is €147 per night from 5 May to 6 May
€147
5 May - 6 May
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Quality Suites Downtown San Luis Obispo. During your stay, you'll be within walking distance of California Polytechnic State University, San Luis Obispo. Enjoy features like free WiFi in public areas, free self-parking and a free manager's reception.
9.4/10 Exceptional! (1,391 reviews)
We have stayed there before and will do so again!

Reviewed on 23 Apr 2026

Opens in a new windowQuality Suites Downtown San Luis Obispo
Madonna Inn

Madonna Inn

3.5 out of 5
100 Madonna Road San Luis Obispo CA
The price is €173 per night from 26 Apr to 27 Apr
€173
26 Apr - 27 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Madonna Inn. During your stay, you're just a quick walk from Laguna Lake Park. Free WiFi in public areas, free self-parking and 2 restaurants are available.
9.2/10 Wonderful! (1,436 reviews)
Such a unique and special property. We had a beautiful view from our room. The restaurants are excellent, too, and the staff is very friendly. We love it there!

Reviewed on 22 Apr 2026

Opens in a new windowMadonna Inn
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3 out of 5
1845 Monterey St. San Luis Obispo CA
The price is €136 per night from 4 May to 5 May
€136
4 May - 5 May
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown. During your stay, you'll be within walking distance of California Polytechnic State University, San Luis Obispo. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.
9/10 Wonderful! (1,944 reviews)
Perfect spot for our quick girls' weekend in SLO.

Reviewed on 21 Apr 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Save an average of 15% on thousands of hotels when you're signed in
Apple Farm

Apple Farm

3.5 out of 5
2015 Monterey St San Luis Obispo CA
The price is €105 per night from 26 Apr to 27 Apr
€105
26 Apr - 27 Apr
includes taxes & fees
Our customers tell us they can't get enough of Apple Farm's great location. During your stay, you'll be within walking distance of California Polytechnic State University, San Luis Obispo. Free WiFi in public areas, an outdoor pool and breakfast (surcharge) are available.
9/10 Wonderful! (1,620 reviews)
Amazingly clean, but not so good with the amenities

Reviewed on 23 Apr 2026

Opens in a new windowApple Farm
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

2.5 out of 5
345 Marsh St San Luis Obispo CA
The price is €81 per night from 27 Apr to 28 Apr
€81
27 Apr - 28 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Avenue Inn Downtown San Luis Obispo. During your stay, you're just a quick walk from Cerro San Luis Obispo. Enjoy features like free WiFi in public areas and free self-parking.
9/10 Wonderful! (1,216 reviews)
Being my first time over in SLO,

Reviewed on 22 Apr 2026

Opens in a new windowAvenue Inn Downtown San Luis Obispo
Mission Inn San Luis Obispo

Mission Inn San Luis Obispo

2 out of 5
1951 Monterey St San Luis Obispo CA
The price is €88 per night from 6 May to 7 May
€88
6 May - 7 May
includes taxes & fees
Our customers tell us they can't get enough of Mission Inn San Luis Obispo's great location. During your stay, you'll be within walking distance of California Polytechnic State University, San Luis Obispo. Enjoy features like free WiFi in public areas and free self-parking, plus a business centre.
8/10 Very Good! (951 reviews)
Very clean

Reviewed on 21 Apr 2026

Opens in a new windowMission Inn San Luis Obispo
Don't see what you're looking for?
See all available properties in San Luis Obispo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.