Pensione Guerrato's proximity to the Grand Canal and Rialto Bridge makes it an ideal home base for excursions, but still in a neighborhood that is peaceful and quiet.
The Gelato place around the corner (Venchi) has the best Gelato I found in Italy (they coat the waffle cones with chocolate of your choice), and the capuccino at Guerrato itself was excellent.
We had to rise early one morning at 5:30 am, before their sumptuous breakfast was served, and the staff was invaluable both in securing a water taxi, and giving us coffee while we waited. Really, it was the perfect spot for our visit to Venice.