Cheap flights from Panama City

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Cheap round-trip flights from Panama City

The lowest prices found within the past 7 days from Panama City to were €258 for one-way flights and €390 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Panama City Flight Information
Origin airport IATA code
PNS

Sourcing the best flights from Panama City on ebookers

If you’re seeking a flight from Panama City, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from PNS. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from PNS

There are a few golden rules for keeping costs low when booking flights from Panama City. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Panama City, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from PNS. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Panama City

Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
The price is €125 per night from 17 May to 18 May
€125
17 May - 18 May
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hilton Garden Inn Panama City Airport. Features include free WiFi in public areas and free self-parking, plus a restaurant.
9.4/10 Exceptional! (749 reviews)
Very close to the airport, clean rooms and facilities. Staff was very nice. Easy check in.

Reviewed on 28 Apr 2026

Opens in a new windowHilton Garden Inn Panama City Airport
La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
The price is €83 per night from 17 May to 18 May
€83
17 May - 18 May
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham Panama City. During your stay, you'll be within walking distance of Linos Park. You'll find features such as free WiFi in public areas and free self-parking, plus a gym. This property offers pet-friendly amenities, such as an off-lead area.
8.8/10 Excellent! (1,013 reviews)
Wasn’t the cleanest

Reviewed on 4 May 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Panama City
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
The price is €81 per night from 17 May to 18 May
€81
17 May - 18 May
includes taxes & fees
During your stay at Comfort Inn & Suites Panama City North, you'll be within walking distance of Junior Museum of Bay County. Free breakfast, free WiFi in public areas and free self-parking are available.
8.2/10 Very Good! (791 reviews)
My room was cool when I checked in, which was nice. The staff was professional and courteous. The location was great, close to everything but quiet at night.

Reviewed on 8 May 2026

Opens in a new windowComfort Inn & Suites Panama City North
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Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
3602 West Hwy 98 Panama City FL
The price is €68 per night from 19 May to 20 May
€68
19 May - 20 May
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Comfort Inn & Suites. During your stay, you're just a quick walk from St. Andrews Bay. Free breakfast, free WiFi in public areas and free self-parking are available.
8.2/10 Very Good! (1,000 reviews)
Staff did not look welcoming and property was dirty.

Reviewed on 28 Apr 2026

Opens in a new windowComfort Inn & Suites
Quality Inn Panama City North

Quality Inn Panama City North

2.5 out of 5
1013 E 23rd St Panama City FL
The price is €67 per night from 19 May to 20 May
€67
19 May - 20 May
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Quality Inn Panama City North. During your stay, you'll be connected to the convention centre and within walking distance of Linos Park. Features include free breakfast, free WiFi in public areas and free self-parking.
7.6/10 Good! (730 reviews)
The room itself was fine. But the bathroom with the toilet and shower was awful! Peeling paint and loose moulding which indicated prior water damage. The frame & track for the shower door was mending with what looked like packing tape. The bathroom smelled strongly of bleach and it looked like there ...

Reviewed on 5 May 2026

Opens in a new windowQuality Inn Panama City North
Red Roof Inn Panama City

Red Roof Inn Panama City

2 out of 5
217 North US Hwy 231 Panama City FL
The price is €75 per night from 7 Jun to 8 Jun
€75
7 Jun - 8 Jun
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Red Roof Inn Panama City. During your stay, you're just a quick walk from Linos Park. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
Opens in a new windowRed Roof Inn Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.