Cheap flights from Panama City

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Panama City Flight Information
Origin airport IATA code
PNS

Sourcing the best flights from Panama City on ebookers

If you’re seeking a flight from Panama City, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from PNS. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from PNS

There are a few golden rules for keeping costs low when booking flights from Panama City. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Panama City, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from PNS. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Panama City

Hotel Indigo Panama City Marina by IHG

Hotel Indigo Panama City Marina by IHG

3.5 out of 5
7 HARRISON AVENUE Panama City FL
The price is €112 per night from 24 Dec to 25 Dec
€112
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hotel Indigo Panama City Marina by IHG. During your stay, you're just a quick walk from Marina Civic Center. You'll find features such as 2 restaurants, an outdoor pool and a 24-hour gym.
9.6/10 Exceptional! (337 reviews)
My recent stay at indigo hotel Panama City was nothing short of exceptional, largely due to two outstanding pillars: flawless cleanliness and truly exemplary staff.

Reviewed on 8 Dec 2025

Opens in a new windowHotel Indigo Panama City Marina by IHG
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
The price is €94 per night from 1 Jan to 2 Jan
€94
1 Jan - 2 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hilton Garden Inn Panama City Airport. Features include free WiFi in public areas and free self-parking, plus a restaurant.
9.4/10 Exceptional! (673 reviews)
Clean and comfy with good service

Reviewed on 18 Dec 2025

Opens in a new windowHilton Garden Inn Panama City Airport
La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
The price is €56 per night from 22 Dec to 23 Dec
€56
22 Dec - 23 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham Panama City. During your stay, you're just a quick walk from Panama City Mall. You'll find features such as free WiFi in public areas and free self-parking, plus a gym. This property offers pet-friendly amenities, such as an off-lead area.
8.6/10 Excellent! (1,001 reviews)
Very clean hotel Easy to find Very spacious room with king bed Safe area, we walked to the nearby mall after dark A great breakfast spread with instant grits, you make waffles, yogurt, fruit, I would definitely stay here again

Reviewed on 16 Dec 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Panama City
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Holiday Inn Panama City by IHG

Holiday Inn Panama City by IHG

3 out of 5
2001 Martin Luther King Boulevard Panama City FL
The price is €81 per night from 28 Dec to 29 Dec
€81
28 Dec - 29 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Holiday Inn Panama City by IHG. During your stay, you're just a quick walk from Panama City Mall. Free WiFi in public areas, free self-parking and an indoor pool are available.
8.6/10 Excellent! (750 reviews)
Room and property was clean and beautiful. Our shower would not work.

Reviewed on 15 Dec 2025

Opens in a new windowHoliday Inn Panama City by IHG
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
The price is €58 per night from 4 Jan to 5 Jan
€58
4 Jan - 5 Jan 2026
includes taxes & fees
During your stay at Comfort Inn & Suites Panama City North, you'll be within walking distance of Panama City Mall. Free breakfast, free WiFi in public areas and free self-parking are available.
8/10 Very Good! (688 reviews)
Great staff, breakfast is delish. Parking and check in very simple and sweet. The rooms are clean and a air and heat, needed this week awesome.

Reviewed on 17 Dec 2025

Opens in a new windowComfort Inn & Suites Panama City North
Econo Lodge Panama City St. Andrews

Econo Lodge Panama City St. Andrews

2 out of 5
4411 W Highway 98 Panama City FL
The price is €48 per night from 4 Jan to 5 Jan
€48
4 Jan - 5 Jan 2026
includes taxes & fees
During your stay at Econo Lodge Panama City St. Andrews, you're just a quick walk from St. Andrews Bay. Features include free breakfast, free WiFi in public areas and free self-parking.
6/10 (450 reviews)
Cleanliness of the floors was not great nice beds typical Motel room, good place to sleep and swim would stay there again if I had to

Reviewed on 28 Jul 2025

Opens in a new windowEcono Lodge Panama City St. Andrews
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.