Cheap flights from Panama City

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Panama City Flight Information
Origin airport IATA code
PNS

Sourcing the best flights from Panama City on ebookers

If you’re seeking a flight from Panama City, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from PNS. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from PNS

There are a few golden rules for keeping costs low when booking flights from Panama City. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Panama City, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from PNS. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Panama City

Hotel Indigo Panama City Marina by IHG

Hotel Indigo Panama City Marina by IHG

3.5 out of 5
7 HARRISON AVENUE Panama City FL
The price is €114 per night from 8 Feb to 9 Feb
€114
per night
8 Feb - 9 Feb
Our customers tell us that they can't get enough of the helpful staff at Hotel Indigo Panama City Marina by IHG. During your stay, you're just a quick walk from Marina Civic Center. You'll find features such as 2 restaurants, an outdoor pool and a 24-hour gym.
9.6/10 Exceptional! (365 reviews)
This was the first time staying at a Hotel Indigo and I was very impressed. From the moment I checked in I felt welcomed along with my little fur ball Gizmo. The room was better than I had imagined and the bar and grill located on the same floor was fantastic. I am already looking for my next getaway ...

Reviewed on 26 Jan 2026

Opens in a new windowHotel Indigo Panama City Marina by IHG
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
The price is €97 per night from 15 Feb to 16 Feb
€97
per night
15 Feb - 16 Feb
Our customers tell us that they can't get enough of the helpful staff at Hilton Garden Inn Panama City Airport. Features include free WiFi in public areas and free self-parking, plus a restaurant.
9.4/10 Exceptional! (697 reviews)
Everything was absolutely amazing. Top to bottom cleanliness the staff couldn’t ask for better. But your coffee get normal coffee that green tea is not gonna cut it. Give us a choice green tea or real coffee.

Reviewed on 1 Feb 2026

Opens in a new windowHilton Garden Inn Panama City Airport
Courtyard by Marriott Panama City

Courtyard by Marriott Panama City

3 out of 5
905 E 23rd Pl Panama City FL
The price is €83 per night from 8 Feb to 9 Feb
€83
per night
8 Feb - 9 Feb
During your stay at Courtyard by Marriott Panama City, you're just a quick walk from Panama City Mall. Free WiFi in public areas, an outdoor pool and a restaurant are available.
9/10 Wonderful! (398 reviews)
The staff was friendly and helpful. The room was very clean! The breakfast was expensive; I had a bowl of oatmeal described as steel cut, but I’m quite certain it was quick oats. The blueberries were good, tho!

Reviewed on 2 Feb 2026

Opens in a new windowCourtyard by Marriott Panama City
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La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
The price is €64 per night from 8 Feb to 9 Feb
€64
per night
8 Feb - 9 Feb
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham Panama City. During your stay, you're just a quick walk from Panama City Mall. You'll find features such as free WiFi in public areas and free self-parking, plus a gym. This property offers pet-friendly amenities, such as an off-lead area.
8.6/10 Excellent! (1,001 reviews)
Well run, friendly, clean and convenient, nice breakfast too.

Reviewed on 28 Jan 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Panama City
Best Western Plus Panama City Hotel

Best Western Plus Panama City Hotel

2.5 out of 5
Mercedes Avenue, 2338 Panama City FL
The price is €67 per night from 8 Feb to 9 Feb
€67
per night
8 Feb - 9 Feb
Our customers tell us that they can't get enough of the free breakfast at Best Western Plus Panama City Hotel. During your stay, you'll be within walking distance of Panama City Mall. Features include free WiFi in public areas and free self-parking, plus an outdoor pool.
8.2/10 Very Good! (890 reviews)
I had a great stay. The room was clean and surprisingly spacious, and the check-in process was smooth and hassle-free. Would stay again.

Reviewed on 16 Jan 2026

Opens in a new windowBest Western Plus Panama City Hotel
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
The price is €64 per night from 8 Feb to 9 Feb
€64
per night
8 Feb - 9 Feb
During your stay at Comfort Inn & Suites Panama City North, you'll be within walking distance of Panama City Mall. Free breakfast, free WiFi in public areas and free self-parking are available.
8/10 Very Good! (714 reviews)
Yes

Reviewed on 26 Jan 2026

Opens in a new windowComfort Inn & Suites Panama City North
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.