Best 4 Star Hotels in Clayton
Check availability on Clayton 4 Star Hotels
Featured Clayton 4 Stars Hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
The price is €88 per night
€88
22 Dec - 23 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Magnolia Hotel St. Louis, a Tribute Portfolio Hotel. During your stay, you're just a quick walk from Busch Stadium. Free WiFi in public areas, a restaurant and a 24-hour gym are available.
Pet-friendly
Free WiFi

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is €99 per night
€99
21 Dec - 22 Dec
includes taxes & fees
The sightseeing around Hyatt Regency St. Louis at The Arch gets high marks from our customers. During your stay, you're just a quick walk from Busch Stadium. Free WiFi in public areas, 3 restaurants and 2 bars are available.

Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
The price is €129 per night
€129
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Hilton St. Louis Frontenac's great location. During your stay, you'll be close to Missouri Baptist Medical Center. You'll find features such as free WiFi in public areas, free self-parking and a free round-trip airport shuttle.
Pool
Free airport shuttle

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is €138 per night
€138
25 Dec - 26 Dec
includes taxes & fees
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from City Museum. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
Pool
Spa

The Cheshire
6300 Clayton Rd Richmond Heights MO
The price is €114 per night
€114
23 Dec - 24 Dec
includes taxes & fees
The free breakfast at The Cheshire gets high marks from our customers. During your stay, you're just a quick walk from Forest Park. Free WiFi in public areas, a restaurant and a 24-hour gym are available. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Breakfast included

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
The price is €118 per night
€118
2 Jan - 3 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Renaissance St. Louis Airport Hotel. During your stay, you'll be close to Blanche M. Touhill Performing Arts Center. Features include a free round-trip airport shuttle, plus an indoor pool and a restaurant.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is €120 per night
€120
26 Dec - 27 Dec
includes taxes & fees
Our customers tell us they can't get enough of Angad Arts Hotel St. Louis, Tapestry Collection by Hilton's great location. During your stay, you're just a quick walk from Fox Theater. You'll find features such as free WiFi in public areas, plus a restaurant and a gym.

Live by Loews - St.Louis
799 Clark ave St. Louis MO
The price is €151 per night
€151
20 Dec - 21 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Live by Loews - St.Louis. During your stay, you're just a quick walk from Busch Stadium. Enjoy features like free WiFi in public areas, plus a restaurant and a gym. This property offers pet-friendly amenities, such as food and water bowls.

The Westin St. Louis
811 Spruce St St. Louis MO
The price is €122 per night
€122
26 Dec - 27 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Westin St. Louis. During your stay, you're just a quick walk from Busch Stadium. A restaurant, a bar and a business centre are available. This property offers pet-friendly amenities, such as food and water bowls.

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
The price is €166 per night
€166
22 Dec - 23 Dec
includes taxes & fees
Our customers tell us that they enjoy the overall property condition at Ameristar Casino Resort and Spa. During your stay, you're just a quick walk from Ameristar Casino St. Charles. 6 restaurants, 2 bars and a full-service spa are available.

DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
The price is €106 per night
€106
15 Jan - 16 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at DoubleTree by Hilton St. Louis Forest Park. During your stay, you're just a quick walk from Forest Park. You'll find features such as free WiFi in public areas, plus a restaurant and a gym.

River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
The price is €111 per night
€111
22 Dec - 23 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at River City Casino & Hotel. During your stay, you're just a quick walk from Mississippi River. Free self-parking, 5 restaurants and a casino are available.

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
The price is €157 per night
€157
25 Dec - 26 Dec
includes taxes & fees
St. Louis Union Station Hotel, Curio Collection by Hilton's great location gets high marks from our customers. During your stay, you're just a quick walk from St. Louis Union Station. Enjoy features like free WiFi in public areas, plus 7 restaurants and 3 bars.
Pool
Pet-friendly

Marriott St. Louis Grand
800 Washington Ave St. Louis MO
The price is €128 per night
€128
23 Dec - 24 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Marriott St. Louis Grand. During your stay, you're just a quick walk from Dome at America’s Center. Free WiFi in public areas, a restaurant and a 24-hour gym are available.

Moonrise Hotel
6177 Delmar Blvd St. Louis MO
The price is €119 per night
€119
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us they can't get enough of Moonrise Hotel's great location. During your stay, you'll be within walking distance of Washington University in St. Louis. Free WiFi in public areas, free self-parking and 2 bars are available. This property offers pet-friendly amenities, such as food and water bowls.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Clayton hotels essential information
Accommodation | 1,810 hotels |
|---|---|
Lowest Price | €88 |
Highest Price | €166 |
Popular hotels | Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Hyatt Regency St. Louis at The Arch, Hilton St. Louis Frontenac, 21C Museum Hotel St Louis , The Cheshire, Renaissance St. Louis Airport Hotel, Angad Arts Hotel St. Louis, Tapestry Collection by Hilton, Live by Loews - St.Louis, The Westin St. Louis, Ameristar Casino Resort and Spa, DoubleTree by Hilton St. Louis Forest Park, River City Casino & Hotel, St. Louis Union Station Hotel, Curio Collection by Hilton, Marriott St. Louis Grand, Moonrise Hotel |
Recent Clayton hotel reviews by travellers like youebookers verified reviews

Le Méridien St. Louis Clayton
5/5 Excellent
"Excellent service "
A verified traveller stayed at Le Méridien St. Louis Clayton
Posted 2 months ago

Hyatt Regency St. Louis at The Arch
5/5 Excellent
"Both bars had great selections!"
A verified traveller stayed at Hyatt Regency St. Louis at The Arch
Posted 5 days ago
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