Best 4 Star Hotels in Otay Mesa
Check availability on Otay Mesa 4 Star Hotels
Featured Otay Mesa 4 Stars Hotels

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is €226 per night
€226
2 Apr - 3 Apr
includes taxes & fees
Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.
Pool
Free WiFi

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
The price is €369 per night
€369
29 Apr - 30 Apr
includes taxes & fees
Manchester Grand Hyatt San Diego's great location gets high marks from our customers. During your stay, you're just a quick walk from Seaport Village. Enjoy features like free WiFi in public areas, plus 6 restaurants and 3 bars.
Pool
Hot tub

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
The price is €289 per night
€289
26 Apr - 27 Apr
includes taxes & fees
Our customers tell us they can't get enough of Paradise Point Resort & Spa's great beach location. During your stay, you'll be close to Mission Bay. Features include free WiFi in public areas, plus 5 outdoor pools and 2 restaurants.
Pool
Hot tub

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd San Diego CA
The price is €246 per night
€246
26 Apr - 27 Apr
includes taxes & fees
Hyatt Regency Mission Bay Spa and Marina's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 2 restaurants. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is €184 per night
€184
2 Apr - 3 Apr
includes taxes & fees
The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from Port of San Diego. Enjoy features like free WiFi in public areas, plus 3 restaurants and an outdoor pool.
Pool
Pet-friendly

San Diego Marriott Gaslamp Quarter
660 K St San Diego CA
The price is €154 per night
€154
5 Apr - 6 Apr
includes taxes & fees
San Diego Marriott Gaslamp Quarter's great location gets high marks from our customers. During your stay, you're just a quick walk from Petco Park. You'll find features such as 2 bars, a restaurant and a 24-hour gym.
Restaurant
Air conditioning

Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
The price is €249 per night
€249
8 Apr - 9 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.
Pool
Pet-friendly

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
The price is €163 per night
€163
4 Apr - 5 Apr
includes taxes & fees
Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from Naval Base Coronado. Free WiFi in public areas, a free round-trip airport shuttle and 3 outdoor pools are available. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Omni San Diego Hotel at the Ballpark
675 L St San Diego CA
The price is €236 per night
€236
3 Apr - 4 Apr
includes taxes & fees
Our customers tell us they can't get enough of Omni San Diego Hotel at the Ballpark's great location. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus an outdoor pool and a restaurant.
Pool
Hot tub

San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
The price is €276 per night
€276
12 Apr - 13 Apr
includes taxes & fees
San Diego Mission Bay Resort's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Features include free WiFi in public areas, plus 2 restaurants and a full-service spa. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Marriott Marquis San Diego Marina
333 W Harbor Dr San Diego CA
The price is €227 per night
€227
6 Apr - 7 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Marriott Marquis San Diego Marina. During your stay, you'll be connected to the convention centre and just a quick walk from Seaport Village. 2 outdoor pools, 5 restaurants and 2 bars are available.
Pool
Hot tub

The Westin San Diego Bayview
1051 Columbia street San Diego CA
The price is €196 per night
€196
5 Apr - 6 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Westin San Diego Bayview. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus an outdoor pool. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Hotel Indigo San Diego-Gaslamp Quarter by IHG
509 9th Ave San Diego CA
The price is €180 per night
€180
5 Apr - 6 Apr
includes taxes & fees
Hotel Indigo San Diego-Gaslamp Quarter by IHG's great location gets high marks from our customers. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 bars. This property offers pet-friendly amenities, such as food and water bowls.
Pet-friendly
Free WiFi

Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
The price is €172 per night
€172
27 Apr - 28 Apr
includes taxes & fees
Legacy Resort Hotel & Spa's great location gets high marks from our customers. During your stay, you're just a quick walk from Hotel Circle. Enjoy features like free WiFi in public areas, plus a full-service spa and an outdoor pool.
Pool
Hot tub

Sentral Gaslamp Quarter
502 10th Avenue San Diego CA
The price is €151 per night
€151
5 Apr - 6 Apr
includes taxes & fees
During your stay at Sentral Gaslamp Quarter, you're just a quick walk from Petco Park. Free WiFi in public areas, a 24-hour gym and a rooftop terrace are available. Built in 2024, this upmarket aparthotel has 131 apartments over 8 floors. Free WiFi and a kitchen are available in each apartment.
Kitchen
Washing machine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa hotels essential information
Accommodation | 4,898 hotels |
|---|---|
Lowest Price | €151 |
Highest Price | €369 |
Popular hotels | Hard Rock Hotel San Diego, Manchester Grand Hyatt San Diego, Paradise Point Resort & Spa, Hyatt Regency Mission Bay Spa and Marina, Wyndham San Diego Bayside, San Diego Marriott Gaslamp Quarter, Lafayette Hotel & Club, Sheraton San Diego Resort, Omni San Diego Hotel at the Ballpark, San Diego Mission Bay Resort, Marriott Marquis San Diego Marina, The Westin San Diego Bayview, Hotel Indigo San Diego-Gaslamp Quarter by IHG, Legacy Resort Hotel & Spa, Sentral Gaslamp Quarter |
Recent Otay Mesa hotel reviews by travellers like youebookers verified reviews

Hard Rock Hotel San Diego
5/5 Excellent
"Great location in the Gaslamp district Ana next to Petco Park!"
A verified traveller stayed at Hard Rock Hotel San Diego
Posted 14 hours ago

Paradise Point Resort & Spa
2/5 Poor
"The deodorizer that was put in the room killed my sinuses which affected me the entire weekend. Oh sure what odor they were trying to kill but it was awful.
The property looked very dated especially the grounds and door frames (looked that there had been some prior forced entrance in front door. "
A verified traveller stayed at Paradise Point Resort & Spa
Posted 9 hours ago
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