Best 4 Star Hotels in Otay Mesa
Check availability on Otay Mesa 4 Star Hotels
Featured Otay Mesa 4 Stars Hotels

Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
The price is €367 per night
€367
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hotel del Coronado, Curio Collection by Hilton. During your stay, you're just a quick walk from Hotel del Coronado. Features include free WiFi in public areas, plus 6 restaurants and 3 bars. This property offers pet-friendly amenities, such as food and water bowls.

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is €207 per night
€207
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.

DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr San Diego CA
The price is €110 per night
€110
3 Jan - 4 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at DoubleTree by Hilton Hotel San Diego - Mission Valley. During your stay, you'll be connected to a shopping centre and within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus an indoor pool and a restaurant.

Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
The price is €132 per night
€132
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Courtyard by Marriott San Diego Downtown Little Italy. During your stay, you're just a quick walk from Waterfront Park. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant. This property offers pet-friendly amenities, such as an off-lead area.

Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
The price is €120 per night
€120
30 Dec - 31 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hilton San Diego Mission Valley. During your stay, you'll be within walking distance of Mission Valley Mall. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.

Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
The price is €149 per night
€149
4 Jan - 5 Jan 2026
includes taxes & fees
Legacy Resort Hotel & Spa's great location gets high marks from our customers. During your stay, you'll be within walking distance of Hotel Circle. Enjoy features like free WiFi in public areas, plus a full-service spa and an outdoor pool.

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is €158 per night
€158
25 Dec - 26 Dec
includes taxes & fees
The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus 3 restaurants.

Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy San Diego CA
The price is €201 per night
€201
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Embassy Suites by Hilton San Diego Bay Downtown. During your stay, you're just a quick walk from Seaport Village. Features include a free manager's reception, plus an indoor pool and a restaurant.

Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
The price is €223 per night
€223
30 Dec - 31 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.

Sheraton Mission Valley San Diego Hotel
1433 Camino Del Rio S San Diego CA
The price is €115 per night
€115
28 Dec - 29 Dec
includes taxes & fees
The shopping around Sheraton Mission Valley San Diego Hotel gets high marks from our customers. During your stay, you'll be within walking distance of Mission Valley Mall. Free WiFi in public areas, an outdoor pool and a restaurant are available. This property offers pet-friendly amenities, such as food and water bowls.

The Westin San Diego Bayview
1051 Columbia street San Diego CA
The price is €166 per night
€166
29 Dec - 30 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Westin San Diego Bayview. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus an outdoor pool. This property offers pet-friendly amenities, such as food and water bowls.

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
The price is €195 per night
€195
24 Dec - 25 Dec
includes taxes & fees
Manchester Grand Hyatt San Diego's great location gets high marks from our customers. During your stay, you're just a quick walk from Seaport Village. Enjoy features like free WiFi in public areas, plus 6 restaurants and 3 bars.

Marriott Marquis San Diego Marina
333 W Harbor Dr San Diego CA
The price is €217 per night
€217
3 Jan - 4 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Marriott Marquis San Diego Marina. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. 2 outdoor pools, 5 restaurants and 2 bars are available.

Margaritaville Hotel San Diego Gaslamp Quarter
435 6th Ave San Diego CA
The price is €184 per night
€184
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us they can't get enough of Margaritaville Hotel San Diego Gaslamp Quarter's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like an outdoor pool, a restaurant and a 24-hour gym. This property offers pet-friendly amenities, such as food and water bowls.

San Diego Marriott Mission Valley
8757 Rio San Diego Dr San Diego CA
The price is €136 per night
€136
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at San Diego Marriott Mission Valley. During your stay, you'll be within walking distance of Snapdragon Stadium. Features include an outdoor pool, a restaurant and a gym.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa hotels essential information
Accommodation | 4,877 hotels |
|---|---|
Lowest Price | €110 |
Highest Price | €367 |
Popular hotels | Hotel del Coronado, Curio Collection by Hilton, Hard Rock Hotel San Diego, DoubleTree by Hilton Hotel San Diego - Mission Valley, Courtyard by Marriott San Diego Downtown Little Italy, Hilton San Diego Mission Valley, Legacy Resort Hotel & Spa, Wyndham San Diego Bayside, Embassy Suites by Hilton San Diego Bay Downtown, Lafayette Hotel & Club, Sheraton Mission Valley San Diego Hotel, The Westin San Diego Bayview, Manchester Grand Hyatt San Diego, Marriott Marquis San Diego Marina, Margaritaville Hotel San Diego Gaslamp Quarter, San Diego Marriott Mission Valley |
Recent Otay Mesa hotel reviews by travellers like youebookers verified reviews

Legacy Resort Hotel & Spa
5/5 Excellent
"El está bien, cómodo, limpio y se mira bastante nuevo, si tuviera que decir algo mal, lo único sería el internet, el que es free no sirve absolutamente para nada prácticamente obligándote a comprar su paquete de internet que la verdad tampoco es que sea muy bueno, pienso que deberían mejorar eso al menos ya que uno está pagando debería ser por algo bueno. En todo lo demás está bastante bien y muy céntrico y cerca de todo. "
A verified traveller stayed at Legacy Resort Hotel & Spa
Posted 2 days ago
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