Best 5 Star Hotels in Lake Nona Medical City
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Check prices in Lake Nona Medical City for tomorrow night, 24 Dec - 25 DecFeatured Lake Nona Medical City 5 Stars Hotels

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
14200 Bonnet Creek Resort Lane Orlando FL
The price is €405 per night
€405
8 Jan - 9 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Waldorf Astoria Orlando - An Official Walt Disney World® Hotel. During your stay, you're just a quick walk from Waldorf Astoria Golf Club. Enjoy features like a free theme park shuttle, plus 2 outdoor pools and 12 restaurants.

Conrad Orlando at Evermore
1500 Eastbeach Way Orlando FL
The price is €596 per night
€596
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Conrad Orlando at Evermore. During your stay, you're just a quick walk from Grand Cypress Golf Club. You'll find features such as 5 restaurants, 3 bars and a full-service spa.

Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort
10100 Dream Tree Blvd. Lake Buena Vista FL
The price is €1,057 per night
€1,057
19 Jan - 20 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort. During your stay, you're just a quick walk from Walt Disney World® Resort. Features include a free theme park shuttle, plus 3 outdoor pools and 5 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

The Ritz-Carlton Orlando, Grande Lakes
4012 Central Florida Parkway Orlando FL
The price is €621 per night
€621
17 Jan - 18 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Ritz-Carlton Orlando, Grande Lakes. During your stay, you'll be within walking distance of The Ritz-Carlton Golf Club. Enjoy features like 7 restaurants, 2 bars and a full-service spa.

ette hotel
3001 Sherberth Rd Kissimmee FL
The price is €416 per night
€416
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at ette hotel. During your stay, you'll be within walking distance of Island H2O Live!. Features include free WiFi in public areas and free valet parking, plus 2 restaurants.

Encore Resort and Water Park at Reunion by Rentyl
7635 Fairfax Dr Kissimmee FL
The price is €616 per night
€616
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Encore Resort and Water Park at Reunion by Rentyl. During your stay, you'll be within walking distance of Jack Nicklaus Course. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.

Reunion Resort & Golf Club
7593 Gathering Drive Kissimmee FL
Our customers tell us that they can't get enough of the helpful staff at Reunion Resort & Golf Club. During your stay, you're just a quick walk from Reunion Resort Golf Course. 11 outdoor pools, 7 restaurants and 2 poolside bars are available. Built in 2005, this luxury aparthotel has 277 apartments. Each apartment includes amenities such as a kitchen and a patio.

Disney's Beach Club Resort
1800 Epcot Resort Blvd Lake Buena Vista FL
During your stay at Disney's Beach Club Resort, you're just a quick walk from Walt Disney World® Resort. Free WiFi in public areas, a free theme park shuttle and 3 outdoor pools are available.

Gorgeous Two Bedroom Apt Close to Disney 306 4721 @Storey Lake Resort
4721 Clock Tower Drive Kissimmee FL
During your stay at this condo building, you'll be within walking distance of Lake Cecile. Features include free WiFi in public areas and free self-parking, plus an indoor pool. The condo offers free WiFi and a private pool.

Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191
3191 Paradox Cir #404 Kissimmee FL
During your stay at this apartment building, you'll be within walking distance of Lake Cecile. Features include free self-parking and free wired Internet, plus an outdoor pool. Free wired Internet and a private pool are available in the apartment.

Stunning 2 Bd Condo Close to Disney 304 3191
3191 Paradox Circle Kissimmee FL
During your stay at this condo building, you'll be within walking distance of Lake Cecile. Free WiFi in public areas, free self-parking and an outdoor pool are available. Enjoy your stay with amenities like free WiFi and a private pool in the condo.

Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131
3131 Paradox Circle Kissimmee FL
During your stay at this holiday home, you'll be within walking distance of Shingle Creek Regional Park. Features include free WiFi in public areas and free self-parking, plus 2 outdoor pools. Free WiFi and a private pool are available in the holiday home.

Gorgeous 4 Bedroom w/ Pool Close to Disney 4836
4836 Dedication Street Kissimmee FL
During your stay at this holiday home, you'll be within walking distance of Lake Cecile. Features include free self-parking and free wired Internet, plus an outdoor pool. Free WiFi and a private pool are available in the holiday home.

Gorgeous 4Bd with Pool @ Storey Lake Resort 4475
4475 Scene Ln Kissimmee FL
During your stay at this holiday home, you'll be within walking distance of Capone's Dinner Show. Features include free self-parking and free wired Internet, plus an outdoor pool. The holiday home offers free wired Internet and a private pool.

7 Bedroom Villa, Private Pool, Resort Amenities
112 Madiera Beach Boulevard Kissimmee FL
During your stay at this villa, you'll be close to Old Town. Free WiFi in public areas, free self-parking and an outdoor pool are available. Enjoy your stay with amenities like free WiFi and a private pool in the villa.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lake Nona Medical City hotels essential information
Accommodation | 27,623 hotels |
|---|---|
Lowest Price | €405 |
Highest Price | €1,057 |
Popular hotels | Waldorf Astoria Orlando - An Official Walt Disney World® Hotel, Conrad Orlando at Evermore, Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort, The Ritz-Carlton Orlando, Grande Lakes, ette hotel, Encore Resort and Water Park at Reunion by Rentyl, Reunion Resort & Golf Club, Disney's Beach Club Resort, Gorgeous Two Bedroom Apt Close to Disney 306 4721 @Storey Lake Resort, Gorgeous 2Bd Apto Close to Disney @ Storey Lake 404 3191, Stunning 2 Bd Condo Close to Disney 304 3191, Luxurious 2 Bd Close to Disney @ Storey Lake 204 3131, Gorgeous 4 Bedroom w/ Pool Close to Disney 4836, Gorgeous 4Bd with Pool @ Storey Lake Resort 4475, 7 Bedroom Villa, Private Pool, Resort Amenities |
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