Best 4 Star Hotels in Lake Nona Medical City
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Check prices in Lake Nona Medical City for tomorrow night, 24 Dec - 25 DecFeatured Lake Nona Medical City 4 Stars Hotels

DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd Orlando FL
The price is €93 per night
€93
15 Jan - 16 Jan 2026
includes taxes & fees
DoubleTree by Hilton at the Entrance to Universal Orlando's great location gets high marks from our customers. During your stay, you're just a quick walk from Universal Orlando Resort. You'll find features such as free WiFi in public areas, plus 2 restaurants and 2 bars.
Pool
Hot tub

Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard Orlando FL
The price is €162 per night
€162
24 Dec - 25 Dec
includes taxes & fees
Hyatt Regency Orlando International Airport's great location gets high marks from our customers. During your stay, you'll be connected to the airport and close to Hoffner Plaza Shopping Center. You'll find features such as free WiFi in public areas, plus 2 restaurants and an outdoor pool.
Pool
Free WiFi

Hyatt Regency Orlando
9801 International Dr Orlando FL
The price is €154 per night
€154
25 Dec - 26 Dec
includes taxes & fees
Hyatt Regency Orlando's great location gets high marks from our customers. During your stay, you'll be connected to the convention centre and just a quick walk from Pointe Orlando. Features include free WiFi in public areas and a free area shuttle, plus 3 restaurants.
Pool
Spa

Walt Disney World Dolphin
1500 Epcot Resort Blvd Lake Buena Vista FL
The price is €245 per night
€245
19 Jan - 20 Jan 2026
includes taxes & fees
Walt Disney World Dolphin's great location gets high marks from our customers. During your stay, you'll be connected to the convention centre and just a quick walk from Disney's Fantasia Gardens Miniature Golf Course. Features include free WiFi in public areas and a free theme park shuttle, plus 3 outdoor pools.
On private beach
Pool

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr Orlando FL
The price is €106 per night
€106
12 Jan - 13 Jan 2026
includes taxes & fees
The shopping around Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando gets high marks from our customers. During your stay, you'll be within walking distance of Lake Bryan. Free WiFi in public areas, 6 outdoor pools and 3 restaurants are available.
Pool
Hot tub

Hilton Orlando Lake Buena Vista - Disney Springs® Area
1751 Hotel Plaza Blvd Lake Buena Vista FL
The price is €183 per night
€183
9 Jan - 10 Jan 2026
includes taxes & fees
Hilton Orlando Lake Buena Vista - Disney Springs® Area's great location gets high marks from our customers. During your stay, you'll be within walking distance of Disney Springs™. Enjoy features like 2 outdoor pools, 6 restaurants and 2 bars.
Pool
Hot tub

DoubleTree by Hilton Hotel Orlando at SeaWorld
10100 International Drive Orlando FL
The price is €90 per night
€90
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the sightseeing around DoubleTree by Hilton Hotel Orlando at SeaWorld. During your stay, you're just a quick walk from Aquatica. You'll find features such as free WiFi in public areas, plus 2 outdoor pools and 2 restaurants.
Pool
Pet-friendly

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
12401 International Dr Orlando FL
The price is €126 per night
€126
12 Jan - 13 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Sheraton Vistana Villages Resort Villas, I-Drive/Orlando's great location. During your stay, you'll be within walking distance of Orlando Vineland Premium Outlets. Enjoy features like free WiFi in public areas, plus 5 outdoor pools and 2 restaurants.
Pool
Hot tub

Courtyard by Marriott Lake Buena Vista at Vista Centre
8501 Palm Pkwy Orlando FL
The price is €93 per night
€93
7 Jan - 8 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Courtyard by Marriott Lake Buena Vista at Vista Centre's great location. During your stay, you'll be within walking distance of Lake Bryan. Features include free WiFi in public areas and a free theme park shuttle, plus 2 outdoor pools.
Pool
Free WiFi

Rosen Shingle Creek
9939 Universal Blvd Orlando FL
The price is €114 per night
€114
23 Jan - 24 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Rosen Shingle Creek's great location. During your stay, you're just a quick walk from Shingle Creek Golf Course. Free WiFi in public areas, a free theme park shuttle and 4 outdoor pools are available.
Pool
Hot tub

Hilton Vacation Club Mystic Dunes Orlando
7600 Mystic Dunes Lane Kissimmee FL
The price is €126 per night
€126
5 Jan - 6 Jan 2026
includes taxes & fees
Hilton Vacation Club Mystic Dunes Orlando's great location gets high marks from our customers. During your stay, you'll be close to Disney's Animal Kingdom® Theme Park. Enjoy features like free WiFi in public areas and free self-parking, plus 4 outdoor pools. This upmarket property has 986 rooms over 6 floors. All rooms offer free WiFi and cable TV channels.
Pool
Parking included

Marriott's Grande Vista
5925 Avenida Vista Orlando FL
The price is €122 per night
€122
13 Jan - 14 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Marriott's Grande Vista's great location. During your stay, you'll be close to Orange County Convention Center. Features include free WiFi in public areas, plus 4 outdoor pools and 3 restaurants.
Pool
Hot tub

DoubleTree by Hilton Orlando Airport
5555 Hazeltine National Drive Orlando FL
The price is €123 per night
€123
24 Dec - 25 Dec
includes taxes & fees
Our customers tell us they can't get enough of DoubleTree by Hilton Orlando Airport's great location. During your stay, you'll be close to Hoffner Plaza Shopping Center. Features include free WiFi in public areas, a free round-trip airport shuttle and a free area shuttle.
Pool
Free airport shuttle

Margaritaville Resort Orlando
8000 Fins Up Circle Kissimmee FL
The price is €181 per night
€181
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Margaritaville Resort Orlando's great location. During your stay, you're just a quick walk from Island H2O Live!. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 3 restaurants.
Pool
Hot tub

Rosen Plaza on International Drive
9700 International Dr Orlando FL
The price is €117 per night
€117
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Rosen Plaza on International Drive. During your stay, you'll be connected to the convention centre and just a quick walk from Pointe Orlando. Features include free WiFi in public areas and a free theme park shuttle, plus 5 restaurants.
Pool
Hot tub
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See all available properties in Lake Nona Medical City
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lake Nona Medical City hotels essential information
Accommodation | 27,623 hotels |
|---|---|
Lowest Price | €90 |
Highest Price | €245 |
Popular hotels | DoubleTree by Hilton at the Entrance to Universal Orlando, Hyatt Regency Orlando International Airport, Hyatt Regency Orlando, Walt Disney World Dolphin, Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando, Hilton Orlando Lake Buena Vista - Disney Springs® Area, DoubleTree by Hilton Hotel Orlando at SeaWorld, Sheraton Vistana Villages Resort Villas, I-Drive/Orlando, Courtyard by Marriott Lake Buena Vista at Vista Centre, Rosen Shingle Creek, Hilton Vacation Club Mystic Dunes Orlando, Marriott's Grande Vista, DoubleTree by Hilton Orlando Airport, Margaritaville Resort Orlando, Rosen Plaza on International Drive |
Recent Lake Nona Medical City hotel reviews by travellers like youebookers verified reviews

DoubleTree by Hilton Hotel Orlando at SeaWorld
5/5 Excellent
"Friendly people "
A verified traveller stayed at DoubleTree by Hilton Hotel Orlando at SeaWorld
Posted 2 days ago
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