Cheap flights from Southern Minnesota

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Southern Minnesota Flight Information
Origin airport IATA code
MSP

Sourcing the best flights from Southern Minnesota on ebookers

If you’re seeking a flight from Southern Minnesota, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from MSP. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from MSP

There are a few golden rules for keeping costs low when booking flights from Southern Minnesota. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Southern Minnesota, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from MSP. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Southern Minnesota

The Berkman

The Berkman

3 out of 5
217 14th Ave SW Rochester MN
The price is €167 per night from 19 Dec to 20 Dec
€167
19 Dec - 20 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Berkman. During your stay, you're just a quick walk from Mayo Clinic Hospital - Saint Marys Campus. You'll find features such as free WiFi in public areas, plus a gym and a snack bar/deli. Built in 2020, this comfortable aparthotel has 80 apartments over 14 floors. This property offers pet-friendly amenities, such as an off-lead area. Each apartment includes amenities such as free WiFi and a kitchen.
9.6/10 Exceptional! (367 reviews)
Apartment was spacious and comfortable and quiet. Woman concierge who checked us in and out was very helpful.

Reviewed on 28 Nov 2025

Opens in a new windowThe Berkman
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
The price is €68 per night from 4 Jan to 5 Jan
€68
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Spark by Hilton Rochester South. During your stay, you'll be within walking distance of Marcus Rochester Cinema. Enjoy features like free breakfast, free WiFi in public areas and free self-parking.
9.2/10 Wonderful! (300 reviews)
Very clean and comfortable. Pillows were very soft.Staff was very courteous.

Reviewed on 5 Dec 2025

Opens in a new windowSpark by Hilton Rochester South
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
The price is €81 per night from 4 Jan to 5 Jan
€81
4 Jan - 5 Jan 2026
includes taxes & fees
The free breakfast at Hampton Inn Rochester-South gets high marks from our customers. During your stay, you'll be within walking distance of OMC FastCare - South. Enjoy features like free WiFi in public areas, free self-parking and a free area shuttle.
9/10 Wonderful! (1,002 reviews)
Staff was very friendly and helpful; room was clean and comfortable. Would stay there again

Reviewed on 3 Dec 2025

Opens in a new windowHampton Inn Rochester-South
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Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
The price is €128 per night from 20 Dec to 21 Dec
€128
20 Dec - 21 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Hyatt House Rochester/Mayo Clinic Area. During your stay, you're just a quick walk from Shops University Square. Features include free WiFi in public areas and a free area shuttle, plus an indoor pool.
9/10 Wonderful! (1,000 reviews)
Clean room, friendly staff, clean and modern lobby, good location to Mayo Clinic

Reviewed on 27 Nov 2025

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
The price is €133 per night from 11 Dec to 12 Dec
€133
11 Dec - 12 Dec
includes taxes & fees
Kahler Grand Hotel's great location gets high marks from our customers. During your stay, you'll be connected to the convention centre and just a quick walk from Shops University Square. Enjoy features like free WiFi in public areas, plus 2 restaurants and an indoor pool.
8.2/10 Very Good! (1,798 reviews)
Perfect located to the Mayo Clinic. Room was very nice . Staff was excellent. Very helpful . Will be back on Sunday and next month .

Reviewed on 5 Dec 2025

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
The price is €138 per night from 10 Dec to 11 Dec
€138
10 Dec - 11 Dec
includes taxes & fees
Kahler Inn and Suites - Mayo Clinic Area's great location gets high marks from our customers. During your stay, you're just a quick walk from American Cancer Society Hope Lodge. Enjoy features like free breakfast and free WiFi in public areas, plus an indoor pool.
7.8/10 Good! (1,514 reviews)
The beds were very comfortable. The rooms were clean. Parking was safe, the only bad thing was that they charged me for parking and I didn't realize that they charged for parking.

Reviewed on 6 Dec 2025

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.