Find 3,892 hotels in San Diego Santa Fe Depot

Our customers tell us they can't get enough of Paradise Point Resort & Spa's great beach location. During your stay, you'll be close to Mission Bay. Features include free WiFi in public areas, plus 5 outdoor pools and 2 restaurants.

Our customers tell us that they can't get enough of the shopping around Best Western Seven Seas. During your stay, you're just a quick walk from Hotel Circle. Free WiFi in public areas, free self-parking and an outdoor pool are available.

Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.

Our customers tell us they can't get enough of Handlery Hotel's great location. During your stay, you'll be within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus 2 restaurants and 2 bars.

Our customers tell us that they can't get enough of the helpful staff at The DEXTRO Little Italy, BW Premier Collection. During your stay, you're just a quick walk from San Diego Civic Theatre. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.

Our customers tell us that they can't get enough of the comfortable beds at Days Inn by Wyndham San Diego Hotel Circle. During your stay, you're just a quick walk from Hotel Circle. Enjoy features like free WiFi in public areas, plus an outdoor pool and a gym.

Manchester Grand Hyatt San Diego's great location gets high marks from our customers. During your stay, you're just a quick walk from Seaport Village. Enjoy features like free WiFi in public areas, plus 6 restaurants and 3 bars.

Our customers tell us that they can't get enough of the helpful staff at The Sofia Hotel. During your stay, you're just a quick walk from San Diego Civic Theatre. Free WiFi in public areas, a restaurant and a 24-hour gym are available. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from San Diego Bay. Free WiFi in public areas, a free round-trip airport shuttle and 3 outdoor pools are available. This property offers pet-friendly amenities, such as food and water bowls.

The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus 3 restaurants.

Our customers tell us that they can't get enough of the shopping around Bahia Resort Hotel. During your stay, you're just a quick walk from Mission Beach. Enjoy features like an outdoor pool, a restaurant and a gym.

The Dana on Mission Bay's great beach location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Beach. Enjoy features like 2 outdoor pools, 2 poolside bars and a restaurant. This property offers pet-friendly amenities, such as food and water bowls.

San Diego Mission Bay Resort's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Features include free WiFi in public areas, plus 2 restaurants and a full-service spa. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us they can't get enough of Bay Club Hotel & Marina's great location. During your stay, you're just a quick walk from Humphreys Concerts by the Bay. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant.

Our customers tell us that they can't get enough of the helpful staff at Hotel del Coronado, Curio Collection by Hilton. During your stay, you're just a quick walk from Coronado Beach. Features include free WiFi in public areas, plus 6 restaurants and 3 bars. This property offers pet-friendly amenities, such as food and water bowls.