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With around 800,000 proud residents, you're bound to meet plenty of new friends!
If you venture 75 miles northeast of San Francisco, you'll hit Sacramento, the state capital. Travel 6 miles northwest and you'll come upon Sausalito.
In a classic tourist destination that's overflowing with things to see and do, Golden Gate Bridge and the University of San Francisco always seem to be the ones visitors remember. You mustn't forget Pier 39 and Lombard Street either!
An afternoon at the Castro Theatre or the San Francisco Mint is a fantastic opportunity for some family bonding. Are the little ones still bouncing off the walls? Keep the excitement going with a trip to the Sundance Kabuki Cinemas and the Presidio Theatre.
Take a deep breath and embark on an underwater adventure at Aquarium of the Bay, where you'll happen upon a variety of creatures of the deep. Yet another oceanic world is waiting for you at Aquarium of the Bay.
Come face-to-face with some amazing animals and learn about the need to protect our environment with a family day trip to the San Francisco Zoo.
Do you and your pals enjoy a few cold ones every now and then? See if there are any scheduled tours and pick the brains of the experienced brewers at the Anchor Brewing Company.
Learn how the best local wines are made, and later sample a handful of them, with a visit to the Winery Collective.
The Artichoke Joe's Casino is the place to go for high-stakes games and an electric atmosphere. Place a bet or two, have a cocktail and take in the pulsing atmosphere.
This region takes its plant collecting seriously, so there are a number of places where you can go and learn all about botanic species from both regional and international landscapes. A wander through the landscaped gardens at the Conservatory of Flowers and the San Francisco Botanical Garden is a must. For those who are more committed, the Dahlia Garden and the Queen Wilhelmina Garden also have some pleasing floral exhibits.
Get comfortable with your favourite book, kick a ball around or just watch the clouds pass overhead at the Palace of Fine Arts and Twin Peaks. Also consider whiling away some time at Golden Gate Park or the Japanese Tea Garden.
Whether you want to discover the hottest restaurant or what to do after dark, you'll find the information you're after at San Francisco Visitor's Centre or Sausalito Visitors Kiosk. Gulf of the Farallones National Marine Sanctuary - Visitor Centre and California Welcome Centre are two more useful places to get the scoop on what to see and do around town.
The tranquil sounds of lapping water and chirping waterbirds at San Francisco Bay Sailing and Stow Lake guarantee you a dreamy afternoon out. If you could do with some more downtime by the waterside, take a trip out to Lake Merced.
There's nothing better than a day spent at the seaside. You're spoilt for choice in this area, with Rockaway Beach and China Beach among the top places to plunge a toe in the water. Travellers who are eager to see more should continue to Baker Beach and Miramar Beach.
You probably know about its must-see museums and malls, but don't forget that San Francisco has some impressive natural havens too. Alcatraz Island and Fisherman's Wharf are two to keep in the front of your mind. Muir Woods and Angel Island are two more that are worth a look.
A crucial area of marine conservation, JV Fitzgerald Marine Reserve is overflowing with underwater activity.
The Exploratorium and the California Academy of Sciences both have a range of fascinating displays. Ask the welcoming staff about one-off events or walk the peaceful halls in your own time. The San Francisco Museum of Modern Art and California Palace of the Legion of Honour are also leading alternatives.
Ship building and navigation techniques have played a massive role in shaping many countries across the world. To find out more about the nautical past of the area, dust of your map and mark a cross on the San Francisco Maritime Museum.
Satisfy your inquisitive mind with a visit to Morrison Planetarium. While you're there, don't forget to enquire about any travelling exhibits. Trust us, you won't want to miss a thing!
We're not exactly sure how the Mexican Museum and the Kimball Natural History Museum have managed to gather so many of this planet's fascinating artifacts into just two spaces. A stop at either will transfix you for hours on end. When it comes to the natural world you'll never experience it all, but there's certainly no harm in trying! For even more exotic specimens, add the Natural World Museum to your itinerary.
Whichever genre of art rocks your socks, there's a chance you'll find it in San Francisco. Why not start your day of gallery hopping at the Asian Art Museum of San Francisco and the De Young Museum? More vibrant canvases and stunning sculptures await you at the Yerba Buena Centre for the Arts and the Cartoon Art Museum.
Step back in time to discover the events and people that have helped shape this area at the Randall Museum and the Museum of the African Diaspora. You can also immerse yourself in intriguing exhibits which help bring history to life at the GLBT History Museum and the Wells Fargo History Museum.
Time spent delving into history is never a worthless exercise. Let the University of California San Francisco and the San Francisco State University give you a deeper insight into the area's past. If you're still looking for more, Coit Tower and the City College of San Francisco should be next on the list.
Lefty O'Doul Bridge and Bay Bridge are enduring crossings that will appeal to any visitors that have an interest in historic structures. Francis "Lefty" O'Doul Bridge offers a way to see San Francisco's waterways from another perspective.
Discover the immense stronghold of Fort Point National Historical Site. Learn about its impressive defence techniques and let your mind run wild visualising the sieges that occurred right under your feet.
Get a fill of both local history and faith at Grace Cathedral and Mission Dolores. St. Patrick Catholic Church and the San Francisco Zen Centre will also appeal to anyone wanting some quiet inner-reflection.
It's better to reflect on your life and say, "Did I really do that?," rather than, "I really wish I had done that." So, while you're in San Francisco you should also pay a visit to some of the less well-known sights, such as the San Francisco Public Library and the Fort Mason. You'll also find plenty to keep you amused at the California Historical Society and Coyote Point Park.
^Savings based on all holiday package bookings with Flight + Hotel made on ebookers.ie from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.