Best 3 Star Hotels in Medical Center District
Check availability on Medical Center District 3 Star Hotels
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Check prices in Medical Center District for tomorrow night, 25 Dec - 26 DecFeatured Medical Center District 3 Stars Hotels

Crockett Hotel
320 Bonham San Antonio TX
The price is €89 per night
€89
6 Jan - 7 Jan 2026
includes taxes & fees
Crockett Hotel's great location gets high marks from our customers. During your stay, you're just a quick walk from River Walk. Free WiFi in public areas, an outdoor pool and a restaurant are available.

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is €86 per night
€86
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham San Antonio Riverwalk. During your stay, you're just a quick walk from River Walk. Enjoy features like free WiFi in public areas, plus an outdoor pool and a gym.

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is €120 per night
€120
1 Jan - 2 Jan 2026
includes taxes & fees
The free breakfast at Drury Plaza Hotel San Antonio Riverwalk gets high marks from our customers. During your stay, you're just a quick walk from River Walk. Free WiFi in public areas, a free manager's reception and an indoor pool are available.
Pool
Hot tub

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is €89 per night
€89
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they enjoy the free breakfast at La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW. During your stay, you'll be close to University of Texas Health and Science Center at San Antonio. Features include free WiFi in public areas, plus an outdoor pool and a gym.
Pool
Hot tub

Spark By Hilton San Antonio Northwest near Six Flags
6755 North Loop 1604 West San Antonio TX
The price is €60 per night
€60
1 Jan - 2 Jan 2026
includes taxes & fees
Spark By Hilton San Antonio Northwest near Six Flags's great location gets high marks from our customers. During your stay, you're just a quick walk from University of Texas at San Antonio. You'll find features such as free breakfast and free WiFi in public areas, plus 2 meeting rooms.
Pool
Breakfast included

Menger Hotel
204 Alamo Plaza San Antonio TX
The price is €100 per night
€100
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Menger Hotel. During your stay, you're just a quick walk from River Walk. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.
Pool
Free WiFi

La Quinta Inn & Suites by Wyndham San Antonio Downtown
100 W. Cesar Chavez Blvd San Antonio TX
The price is €81 per night
€81
18 Jan - 19 Jan 2026
includes taxes & fees
The free breakfast at La Quinta Inn & Suites by Wyndham San Antonio Downtown gets high marks from our customers. During your stay, you're just a quick walk from San Antonio River. Free WiFi in public areas, free self-parking and an outdoor pool are available.

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
The price is €107 per night
€107
11 Jan - 12 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Hyatt Vacation Club at Wild Oak Ranch, San Antonio. During your stay, you'll be within walking distance of Hill Country Golf Club. Features include free WiFi in public areas and free self-parking, plus an indoor pool.
Pool
Hot tub

Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
The price is €88 per night
€88
11 Jan - 12 Jan 2026
includes taxes & fees
The free breakfast at Sonesta ES Suites San Antonio Downtown Alamo Plaza gets high marks from our customers. During your stay, you're just a quick walk from River Walk. Features include free WiFi in public areas, plus a gym and a snack bar/deli. This property offers pet-friendly amenities, such as food and water bowls.

La Quinta Inn & Suites By Wyndham San Antonio At The Rim
17910 La Cantera Parkway San Antonio TX
The price is €89 per night
€89
11 Jan - 12 Jan 2026
includes taxes & fees
During your stay at La Quinta Inn & Suites By Wyndham San Antonio At The Rim, you're just a quick walk from The Rim Shopping Center. Features include free breakfast, free WiFi in public areas and free self-parking.
Pool
Breakfast included

Embassy Suites San Antonio Riverwalk-Downtown
125 E Houston St San Antonio TX
The price is €140 per night
€140
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Embassy Suites San Antonio Riverwalk-Downtown. During your stay, you're just a quick walk from River Walk. A free manager's reception, an outdoor pool and a restaurant are available.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham San Antonio Airport
850 Halm Blvd San Antonio TX
The price is €75 per night
€75
7 Jan - 8 Jan 2026
includes taxes & fees
Our customers tell us that they enjoy the free breakfast at La Quinta Inn & Suites by Wyndham San Antonio Airport. During your stay, you'll be within walking distance of North Star Mall. Enjoy features like free WiFi in public areas, free self-parking and a free round-trip airport shuttle.
Pool
Hot tub

Holiday Inn San Antonio - Riverwalk by IHG
217 North St. Mary's Street San Antonio TX
The price is €93 per night
€93
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Holiday Inn San Antonio - Riverwalk by IHG's great location. During your stay, you're just a quick walk from San Antonio River. Free WiFi in public areas, an outdoor pool and a restaurant are available.
Pool
Hot tub

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
11605 State Highway 151 San Antonio TX
The price is €85 per night
€85
29 Dec - 30 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Courtyard by Marriott San Antonio SeaWorld - Westover Hills. During your stay, you'll be within walking distance of Westover Hills Lung Center. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
Pool
Hot tub

Hyatt Place San Antonio–North/Stone Oak
1610 E Sonterra Blvd San Antonio TX
The price is €99 per night
€99
21 Jan - 22 Jan 2026
includes taxes & fees
The breakfast at Hyatt Place San Antonio–North/Stone Oak gets high marks from our customers. During your stay, you're just a quick walk from Methodist Hospital Stone Oak. Features include free WiFi in public areas and free self-parking, plus a 24-hour gym.
Pet-friendly
Parking included
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See all available properties in Medical Center District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Medical Center District hotels essential information
Accommodation | 4,722 hotels |
|---|---|
Lowest Price | €60 |
Highest Price | €140 |
Popular hotels | Crockett Hotel, La Quinta Inn & Suites by Wyndham San Antonio Riverwalk, Drury Plaza Hotel San Antonio Riverwalk, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW, Spark By Hilton San Antonio Northwest near Six Flags, Menger Hotel, La Quinta Inn & Suites by Wyndham San Antonio Downtown, Hyatt Vacation Club at Wild Oak Ranch, San Antonio, Sonesta ES Suites San Antonio Downtown Alamo Plaza, La Quinta Inn & Suites By Wyndham San Antonio At The Rim, Embassy Suites San Antonio Riverwalk-Downtown, La Quinta Inn & Suites by Wyndham San Antonio Airport, Holiday Inn San Antonio - Riverwalk by IHG, Courtyard by Marriott San Antonio SeaWorld - Westover Hills, Hyatt Place San Antonio–North/Stone Oak |
Recent Medical Center District hotel reviews by travellers like youebookers verified reviews

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
5/5 Excellent
"Room was clean and ready for our stay. Breakfast was good and staff very friendly from the moment we walked in to check in. The bed was a little in the stiff side but that won’t stop me from coming back again. I really like the area and the ease to get to dining and shopping options. "
A verified traveller stayed at La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Posted 3 days ago
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