Cheap flights from Rochester

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Rochester Flight Information
Origin airport IATA code
RST

Sourcing the best flights from Rochester on ebookers

If you’re seeking a flight from Rochester, you can swiftly and easily find exactly what you’re looking for using ebookers. Our easy-to-use tool will let you select the destination and ideal travel dates to immediately see which routes and airlines are available. Have a preferred airline in mind for the trip? You can filter your ebookers search to see if they have flights from RST. For more bespoke options, you can also set your search for multiple destinations and flights that are refundable, so you can have the most relevant information in moments.

Getting the best deal on a cheap flight from RST

There are a few golden rules for keeping costs low when booking flights from Rochester. The first thing to think about is being flexible on your travel dates. It can help to shift your departure by a day, or even a few hours, as prices can vary by significant amounts. Use ebookers to compare and contrast your options ahead of time, and you can make a savvy decision. Want more savings? If book the hotel at your chosen destination through ebookers while also arranging your flight from Rochester, you can get a discount of up to 15% off the total price. For help on which pad to pick, you can make use of our snappy hotel descriptions, which are accompanied by useful photos.

Getting things going at your destination

With ebookers, you don’t just have access to the latest, constantly updated information on flights from RST. You can also get inspiration on the most interesting things to get up to when you’re there. Just check out our Things to Do tool and you’ll soon be drawing up an exciting itinerary. And if you’re keen to take in as much of the wider area as possible, you could also look into the best car hire deals and have your very own set of wheels waiting, so you can roam to your heart’s content.

Featured Hotels near Rochester

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
The price is €117 per night from 6 Feb to 7 Feb
€117
6 Feb - 7 Feb
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at EVEN Hotel Rochester - Mayo Clinic Area by IHG. During your stay, you're just a quick walk from Mayo Clinic Hospital - Saint Marys Campus. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
9.2/10 Wonderful! (988 reviews)
Nice room good parking everything was clean..

Reviewed on 28 Jan 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Our customers tell us that they can't get enough of the helpful staff at Aspen Suites. During your stay, you're just a quick walk from Mayo Clinic Hospital - Saint Marys Campus. Features include free breakfast, free WiFi in public areas and free self-parking.
9/10 Wonderful! (714 reviews)
Wonderful all the way around. The staff was friendly, the hotel was clean and well kept, the location was perfect, and the hot tub was just what we wanted after a long day.

Reviewed on 2 Feb 2026

Opens in a new windowAspen Suites
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
The price is €135 per night from 7 Feb to 8 Feb
€135
7 Feb - 8 Feb
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Hyatt House Rochester/Mayo Clinic Area. During your stay, you're just a quick walk from Shops University Square. Features include free WiFi in public areas and a free area shuttle, plus an indoor pool.
9/10 Wonderful! (1,011 reviews)
Front desk was a huge help and extremely kind to us during our visit to Mayo Clinic

Reviewed on 24 Jan 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
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Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
The price is €96 per night from 21 Feb to 22 Feb
€96
21 Feb - 22 Feb
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hotel Indigo Rochester – Mayo Clinic Area by IHG. During your stay, you'll be connected to the convention centre and just a quick walk from Shops University Square. Features include free WiFi in public areas, plus a restaurant and a gym.
8.8/10 Excellent! (922 reviews)
Great room. Nice that checkout is noon. Having Crave Restaurant downstairs is great too.

Reviewed on 20 Jan 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Kahler Grand Hotel's great location gets high marks from our customers. During your stay, you'll be connected to the convention centre and just a quick walk from Shops University Square. Enjoy features like free WiFi in public areas, plus 2 restaurants and an indoor pool.
8.2/10 Very Good! (1,863 reviews)
Room was great. Clean . Bed way too soft.

Reviewed on 29 Jan 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
The price is €72 per night from 22 Feb to 23 Feb
€72
22 Feb - 23 Feb
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at AmericInn by Wyndham Rochester Near Mayo Clinic. During your stay, you're just a quick walk from OMC FastCare - South. Free breakfast, free WiFi in public areas and free self-parking are available.
8/10 Very Good! (1,195 reviews)
Clean, friendly, warm.

Reviewed on 28 Jan 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.